Evidence map›Paper›PMID 37836657›Full record

ArticleMolecules (Basel, Switzerland)2023

Development of a New Benzofuran-Pyrazole-Pyridine-Based Molecule for the Management of Osteoarthritis.

Somaia S Abd El-Karim, Ahlam H Mahmoud, Asmaa K Al-Mokaddem, Noha E Ibrahim, Hamad M Alkahtani, Amer Alhaj Zen, Manal M Anwar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Design, synthesis, andRSC advances · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Somaia S Abd El-KarimDepartment of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre (NRC), El Bohouth St., Dokki, Cairo 12622, Egypt.
Ahlam H MahmoudDepartment of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre (NRC), El Bohouth St., Dokki, Cairo 12622, Egypt.ORCID 0000-0002-8703-841X
Asmaa K Al-MokaddemDepartment of Pathology, Faculty of Veterinary Medicine, Cairo University, Cairo 12211, Egypt.ORCID 0000-0001-6365-8430
Noha E IbrahimDepartment of Microbial Biotechnology, Biotechnology Research Institute, National Research Centre (NRC), El Bohouth St., Dokki, Cairo 12622, Egypt.ORCID 0000-0002-7176-4687
Hamad M AlkahtaniDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-6983-8587
Amer Alhaj ZenChemistry & Forensics Department, Clifton Campus, Nottingham Trent University, Nottingham NG11 8NS, UK.ORCID 0000-0002-4563-0351
Manal M AnwarDepartment of Therapeutic Chemistry, Pharmaceutical and Drug Industries Research Institute, National Research Centre (NRC), El Bohouth St., Dokki, Cairo 12622, Egypt.
National Research Centre · EGCairo University · EGKing Saud University · SANottingham Trent University · GB

Funding

Project number (RSPD2023R930), King Saud University, Riyadh, Saudi Arabia RSPD2023R930
6 · The paper itself

Abstract

Osteoarthritis is a substantial burden for patients with the disease. The known medications for the disease target the mitigation of the disease's symptoms. So, drug development for the management of osteoarthritis represents an important challenge in the medical field. This work is based on the development of a new benzofuran-pyrazole-pyridine-based compound

Indexed as

BenzofuransOsteoarthritisAnimalsAnti-Inflammatory AgentsHumansPyrazolesPyridinesRatsAnti-Inflammatory AgentsBenzofuransPyrazolesPyridinesantioxidanthistopathologyosteoarthritispro-inflammatory mediatorssynthesis

Identifiers

PMID37836657
PMCPMC10574112
OpenAlexW4387105031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.