Evidence map›Paper›PMID 37836548›Full record

Trial reportNutrients2023

The Acute Effect of Hydroxychloroquine Sulfate on Hunger, the Plasma Concentration of Orexigenic Peptides and Hedonic Food Intake: A Pilot Study.

Emily Ruilova Sosoranga, Wout Verbeure, Hannelore Geysen, Theo Thijs, Christophe Matthys, Inge Depoortere, Jan Tack

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Emily Ruilova SosorangaTranslational Research Center for Gastrointestinal Disorders, KU Leuven, 3000 Leuven, Belgium.
Wout VerbeureTranslational Research Center for Gastrointestinal Disorders, KU Leuven, 3000 Leuven, Belgium.
Hannelore GeysenTranslational Research Center for Gastrointestinal Disorders, KU Leuven, 3000 Leuven, Belgium.
Theo ThijsTranslational Research Center for Gastrointestinal Disorders, KU Leuven, 3000 Leuven, Belgium.
Christophe MatthysClinical and Experimental Endocrinology, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0003-1770-6862
Inge DepoortereTranslational Research Center for Gastrointestinal Disorders, KU Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-0289-2175
Jan TackTranslational Research Center for Gastrointestinal Disorders, KU Leuven, 3000 Leuven, Belgium.
KU Leuven · BE

Funding

Methusalem ZKE1114-23-w01Research Foundation - Flanders ZKD2077UEG research price 2015
6 · The paper itself

Abstract

The direct infusion of bitter solutions in the gastrointestinal tract can reduce the secretion of orexigenic hormones and influence appetite and food intake. We aimed to explore whether oral ingestion of the bitter tastant hydroxychloroquine sulfate can exert similar effects. Ten lean adult women were included in this double-blind, randomized, two-visit, crossover study. After an overnight fast, each volunteer received film-coated tablets containing 400 mg of hydroxychloroquine sulfate (Plaquenil

Indexed as

HungerInsulinsAdultAppetiteCross-Over StudiesDouble-Blind MethodEatingEnergy IntakeFemaleGhrelinHumansHydroxychloroquineMotilinPilot ProjectsGhrelinHydroxychloroquineInsulinsMotilinappetitebitterfastingghrelinhydroxychloroquine sulfatemotilinPlaquenil®quinine

Identifiers

PMID37836548
PMCPMC10574275
OpenAlexW4387365061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.