Evidence map›Paper›PMID 37836491›Full record

ArticleNutrients2023

Konjac Glucomannan Counteracted the Side Effects of Excessive Exercise on Gut Microbiome, Endurance, and Strength in an Overtraining Mice Model.

Yu-Heng Mao, Minghan Wang, Yu Yuan, Jing-Kun Yan, Yanqun Peng, Guoqin Xu, Xiquan Weng

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yu-Heng MaoSchool of Exercise and Health, Guangzhou Sport University, Guangzhou 510500, China.ORCID 0000-0002-9602-9910
Minghan WangSchool of Exercise and Health, Guangzhou Sport University, Guangzhou 510500, China.
Yu YuanSchool of Exercise and Health, Guangzhou Sport University, Guangzhou 510500, China.ORCID 0000-0003-1032-6330
Jing-Kun YanEngineering Research Center of Health Food Design & Nutrition Regulation, Dongguan Key Laboratory of Typical Food Precision Design, China National Light Industry Key Laboratory of Healthy Food Development and Nutrition Regulation, School of Life and Health Technology, Dongguan University of Technology, Dongguan 523808, China.ORCID 0000-0001-9547-3772
Yanqun PengSchool of Exercise and Health, Guangzhou Sport University, Guangzhou 510500, China.
Guoqin XuSchool of Exercise and Health, Guangzhou Sport University, Guangzhou 510500, China.ORCID 0000-0003-1858-6997
Xiquan WengSchool of Exercise and Health, Guangzhou Sport University, Guangzhou 510500, China.
Guangzhou Sport University · CNDongguan University of Technology · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2023A1515010004National Natural Science Foundation of China 82003434
6 · The paper itself

Abstract

Excessive exercise without adequate rest can lead to overtraining syndrome, which manifests a series of side effects, including fatigue, gut dysbiosis, and decremental sports performance. Konjac glucomannan (KGM) is a plant polysaccharide with numerous health-improving effects, but few studies reported its effects on the gut microbiome, endurance, and strength in an overtraining model. This study assessed the effect of KGM on gut microbiome, endurance, and strength in mice with excessive exercise. Three doses of KGM (1.25, 2.50, and 5.00 mg/mL) were administrated in drinking water to mice during 42 days of a treadmill overtraining program. The results showed that excessive exercise induced a significant microbial shift compared with the control group, while a high dose (5.00 mg/mL) of KGM maintained the microbial composition. The proportion of

Indexed as

Gastrointestinal MicrobiomeAnimalsFecesMannansMicePolysaccharides(1-6)-alpha-glucomannanMannansPolysaccharidesdietary fibermicrobiotaperformancepolysaccharidesprebiotics

Identifiers

PMID37836491
PMCPMC10574454
OpenAlexW4387185619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.