ArticleNanomaterials (Basel, Switzerland)2023
The Impact of Adding Chitosan Nanoparticles on Biofilm Formation, Cytotoxicity, and Certain Physical and Mechanical Aspects of Directly Printed Orthodontic Clear Aligners.
Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Antimicrobial effect of treating thermoformable cellulose-based materials with essential oils.Clinical oral investigations · 2026Article
- Assessment of biofilm resistance, degree of conversion, and mechanical properties of nanomodified 3D-printed orthodontic clear aligner (in-vitro study).BMC oral health · 2026Article
- Towards standardizing cytotoxicity testing of 3D-printed orthodontic aligners and retainers: a scoping review.Progress in orthodontics · 2026Article
- Next-Generation Orthodontics: Functional Resins, Biomechanics, Biocompatibility, and Current Clinical Reality of Direct 3D-Printed Aligners.Journal of functional biomaterials · 2026Review
- Health and environmental hazards of shape memory polymer used in orthodontic aligners - a scoping review.Biomaterial investigations in dentistry · 2026Review
- Advances in clear aligner therapy: comparative evaluation of the optical properties and bacterial adhesion of 3D direct-printed and thermoformed aligners.Progress in orthodontics · 2025Article
- 3D Printing of Shape Memory Resin for Orthodontic Aligners with Green Synthesized Antimicrobial ZnO Nanoparticles Coatings: Toward Bioactive Devices.Bioengineering (Basel, Switzerland) · 2025Article
- Applications of Growth Factors in Implant Dentistry.Current issues in molecular biology · 2025Review
- Static and dynamic mechanical properties of 3D-printed clear resin with embedded orthodontic metal wire.Progress in orthodontics · 2025Article
- Article
- Applications of chitosan in oral health and diseases.Frontiers in oral health · 2025Review
- Dynamics of the oral microbiome during orthodontic treatment and antimicrobial advances for orthodontic appliances.iScience · 2024Review
- Article
- Article
- Conformation Effect on the Mechanical and Microbiological Behavior of Invisible Orthodontic Aligners.Materials (Basel, Switzerland) · 2024Article
- Biomimetic Coatings in Implant Dentistry: A Quick Update.Journal of functional biomaterials · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aligner treatment is associated with bacterial colonization, leading to enamel demineralization. Chitosan nanoparticles have been demonstrated to have antibacterial properties. This in vitro study aims to determine the effect of adding chitosan nanoparticles to directly 3D-printed clear aligner resin with regard to antibiofilm activity, cytotoxicity, degree of conversion, accuracy, deflection force, and tensile strength. Different concentrations (2%, 3%, and 5%
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.