Evidence map›Paper›PMID 37836057›Full record

ArticlePolymers2023

Mesostructured Fibrils Exfoliated in Deep Eutectic Solvent as Building Blocks of Collagen Membranes.

Ying Pei, Wei Li, Lu Wang, Jing Cui, Lu Li, Shengjie Ling, Keyong Tang, Huafeng Tian

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ying PeiKey Laboratory of Auxiliary Chemistry and Technology for Chemical Industry, Ministry of Education, Shaanxi University of Science and Technology, Xi'an 710021, China.
Wei LiCollege of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China.
Lu WangCollege of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China.
Jing CuiSchool of Physical Science and Technology, Shanghai Tech University, Shanghai 201210, China.
Lu LiKey Laboratory of Auxiliary Chemistry and Technology for Chemical Industry, Ministry of Education, Shaanxi University of Science and Technology, Xi'an 710021, China.ORCID 0000-0003-0963-5670
Shengjie LingSchool of Physical Science and Technology, Shanghai Tech University, Shanghai 201210, China.ORCID 0000-0003-1156-0479
Keyong TangCollege of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China.
Huafeng TianKey Laboratory of Processing and Quality Evaluation Technology of Green Plastics of China National Light Industry Council, Beijing Technology and Business University, Beijing 100048, China.
Zhengzhou University · CNBeijing Technology and Business University · CNShanghaiTech University · CNShaanxi University of Science and Technology · CN

Funding

Henan Science Foundation for Distinguished Young Scholars 222300420074National Natural Science Foundation of China 52173108the fund of Key Laboratory of Auxiliary Chemistry and Technology for Chemical Industry KFKT2020-02the fund of Key Laboratory of Processing and Quality Evaluation Technology of Green Plastics of China National Light Industry Council PQETGP2022004
6 · The paper itself

Abstract

The mesoscale components of collagen (nanofibrils, fibrils, and fiber bundles) are well organized in native tissues, resulting in superior properties and diverse functions. In this paper, we present a simple and controlled liquid exfoliation method to directly extract medium-sized collagen fibers ranging from 102 to 159 nm in diameter from bovine Achilles tendon using urea/hydrochloric acid and a deep eutectic solvent (DES). In situ observations under polarized light microscopy (POM) and molecular dynamics simulations revealed the effects of urea and GuHCl on tendon collagen. FTIR study results confirmed that these fibrils retained the typical structural characteristics of type I collagen. These shed collagen fibrils were then used as building blocks to create independent collagen membranes with good and stable mechanical properties, excellent barrier properties, and cell compatibility. A new method for collagen processing is provided in this work by using DES-assisted liquid exfoliation for constructing robust collagen membranes with mesoscale collagen fibrils as building blocks.

Indexed as

bovine Achilles tendoncollagendeep eutectic solventexfoliationfibrils

Identifiers

PMID37836057
PMCPMC10574992
OpenAlexW4387408058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.