Evidence map›Paper›PMID 37835937›Full record

ArticlePolymers2023

Gentamicin Release Study in Uniaxial and Coaxial Polyhydroxybutyrate-Polyethylene Glycol-Gentamicin Microfibers Treated with Atmospheric Plasma.

Josselyne Transito-Medina, Edna Vázquez-Vélez, Marilú Chávez Castillo, Horacio Martínez, Bernardo Campillo

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Josselyne Transito-MedinaNanotechnology, Academic Division of Industrial Mechanics, Emiliano Zapata Technological University of the State of Morelos, Emiliano Zapata 62765, Mexico.ORCID 0009-0007-5378-4207
Edna Vázquez-VélezSpectroscopy Laboratory, Institute of Physical Sciences, National Autonomous University of Mexico, Av. Universidad #1000, Col. Chamilpa, Cuernavaca 62210, Mexico.ORCID 0000-0002-2154-0116
Marilú Chávez CastilloNanotechnology, Academic Division of Industrial Mechanics, Emiliano Zapata Technological University of the State of Morelos, Emiliano Zapata 62765, Mexico.
Horacio MartínezSpectroscopy Laboratory, Institute of Physical Sciences, National Autonomous University of Mexico, Av. Universidad #1000, Col. Chamilpa, Cuernavaca 62210, Mexico.ORCID 0000-0002-0695-3457
Bernardo CampilloSpectroscopy Laboratory, Institute of Physical Sciences, National Autonomous University of Mexico, Av. Universidad #1000, Col. Chamilpa, Cuernavaca 62210, Mexico.
Universidad Nacional Autónoma de México · MXUniversidad Tecnológica Emiliano Zapata del Estado de Morelos

Funding

DGAPA UNAM IN-102222
6 · The paper itself

Abstract

The skin is the largest organ and one of the most important in the human body, and is constantly exposed to pathogenic microorganisms that cause infections; then, pharmacological administration is required. One of the basic medical methods for treating chronic wounds is to use topical dressings with characteristics that promote wound healing. Fiber-based dressings mimic the local dermal extracellular matrix (ECM), maintaining an ideal wound-healing climate. This work proposes electrospun PHB/PEG polymeric microfibers as dressings for administering the antibiotic gentamicin directed at skin infections. PHB-PEG/gentamicin fibers were characterized before and after plasma treatment by Raman spectroscopy, FTIR, and XRD. SEM was used to evaluate fiber morphology and yarn size. The plasma treatment improved the hydrophilicity of the PHB/PEG/gentamicin fibers. The release of gentamicin in the plasma-treated fibers was more sustained over time than in the untreated ones.

Indexed as

drug deliveryelectrospun fibersgentamicinmodification plasmaPHB-PEG

Identifiers

PMID37835937
PMCPMC10575239
OpenAlexW4387054568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.