Evidence map›Paper›PMID 37835893›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Evaluating Deep Q-Learning Algorithms for Controlling Blood Glucose in In Silico Type 1 Diabetes.

Miguel Tejedor, Sigurd Nordtveit Hjerde, Jonas Nordhaug Myhre, Fred Godtliebsen

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miguel TejedorNorwegian Centre for E-Health Research, P.O. Box 35, N-9038 Tromsø, Norway.
Sigurd Nordtveit HjerdeFaculty of Science and Technology, Norwegian University of Life Sciences, Postboks 5003 NMBU, 1432 Ås, Norway.
Jonas Nordhaug MyhreNORCE Norwegian Research Centre, Postboks 22, Nygårdstangen, 5838 Bergen, Norway.ORCID 0000-0001-9139-1454
Fred GodtliebsenDepartment of Mathematics and Statistics, UiT-The Arctic University of Norway, P.O. Box 6050 Langnes, N-9037 Tromsø, Norway.

Funding

Tromsø research foundation A3327
6 · The paper itself

Abstract

Patients with type 1 diabetes must continually decide how much insulin to inject before each meal to maintain blood glucose levels within a healthy range. Recent research has worked on a solution for this burden, showing the potential of reinforcement learning as an emerging approach for the task of controlling blood glucose levels. In this paper, we test and evaluate several deep Q-learning algorithms for automated and personalized blood glucose regulation in an in silico type 1 diabetes patient with the goal of estimating and delivering proper insulin doses. The proposed algorithms are model-free approaches with no prior information about the patient. We used the Hovorka model with meal variation and carbohydrate counting errors to simulate the patient included in this work. Our experiments compare different deep Q-learning extensions showing promising results controlling blood glucose levels, with some of the proposed algorithms outperforming standard baseline treatment.

Indexed as

artificial pancreasdeep learningQ-learningreinforcement learningtype 1 diabetes

Identifiers

PMID37835893
PMCPMC10572616

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.