Evidence map›Paper›PMID 37835877›Full record

ArticleDiagnostics (Basel, Switzerland)2023

A Bayesian Inference Based Computational Tool for Parametric and Nonparametric Medical Diagnosis.

Theodora Chatzimichail, Aristides T Hatjimihail

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. A software tool for applying Bayes' theorem in medical diagnostics.BMC medical informatics and decision making · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution.

Theodora ChatzimichailHellenic Complex Systems Laboratory, Kostis Palamas 21, 66131 Drama, Greece.ORCID 0000-0001-6765-8454
Aristides T HatjimihailHellenic Complex Systems Laboratory, Kostis Palamas 21, 66131 Drama, Greece.ORCID 0000-0002-0502-7996
Hellenic Complex Systems Laboratory

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical diagnosis is the basis for treatment and management decisions in healthcare. Conventional methods for medical diagnosis commonly use established clinical criteria and fixed numerical thresholds. The limitations of such an approach may result in a failure to capture the intricate relations between diagnostic tests and the varying prevalence of diseases. To explore this further, we have developed a freely available specialized computational tool that employs Bayesian inference to calculate the posterior probability of disease diagnosis. This novel software comprises of three distinct modules, each designed to allow users to define and compare parametric and nonparametric distributions effectively. The tool is equipped to analyze datasets generated from two separate diagnostic tests, each performed on both diseased and nondiseased populations. We demonstrate the utility of this software by analyzing fasting plasma glucose, and glycated hemoglobin A1c data from the National Health and Nutrition Examination Survey. Our results are validated using the oral glucose tolerance test as a reference standard, and we explore both parametric and nonparametric distribution models for the Bayesian diagnosis of diabetes mellitus.

Indexed as

Bayesian diagnosisBayesian inferencecopula distributiondiabetes mellituskernel density estimatorlikelihoodnonparametric distributionparametric distributionposterior probabilityprior probabilityprobability density function

Identifiers

PMID37835877
PMCPMC10572594
OpenAlexW4387376652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.