Evidence map›Paper›PMID 37835791›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Killer Cell Immunoglobulin-like Receptor Genotypes and Reproductive Outcomes in a Group of Infertile Women: A Romanian Study.

Mihai Surcel, Iulia Adina Neamtiu, Daniel Muresan, Iulian Goidescu, Adelina Staicu, Monica Mihaela Marta, Georgiana Nemeti, Radu Harsa, Bogdan Doroftei, Mihai Emil Capilna and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Mihai Surcel1st Department of Obstetrics and Gynecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347 Cluj-Napoca, Romania.
Iulia Adina NeamtiuHealth Department, Environmental Health Center, Part of ALS, 58 Busuiocului Street, 400240 Cluj-Napoca, Romania.ORCID 0000-0002-5314-0539
Daniel Muresan1st Department of Obstetrics and Gynecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347 Cluj-Napoca, Romania.
Iulian Goidescu1st Department of Obstetrics and Gynecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347 Cluj-Napoca, Romania.ORCID 0000-0002-6106-816X
Adelina Staicu1st Department of Obstetrics and Gynecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347 Cluj-Napoca, Romania.
Monica Mihaela MartaDepartment of Medical Education, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347 Cluj-Napoca, Romania.ORCID 0000-0003-2153-4493
Georgiana Nemeti1st Department of Obstetrics and Gynecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347 Cluj-Napoca, Romania.ORCID 0000-0002-8567-1246
Radu HarsaIn Vitro fertilization Department, "Regina Maria" Hospital, 29 Dorobantilor Street, 400117 Cluj-Napoca, Romania.
Bogdan DorofteiFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania.ORCID 0000-0002-6618-141X
Mihai Emil Capilna1st Department of Obstetrics and Gynecology, University of Medicine, Pharmacy Science and Technology "George Emil Palade", 38 Gheorghe Marinescu, 540142 Targu Mures, Romania.ORCID 0000-0001-5661-2514
Gabriela Caracostea1st Department of Obstetrics and Gynecology, "Iuliu Hatieganu" University of Medicine and Pharmacy, 3-5 Clinicilor Street, 400347 Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · ROBabeș-Bolyai University · ROClinical Emergency Hospital Bucharest · ROGrigore T. Popa University of Medicine and Pharmacy · ROUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RO

Funding

Ministry of Research, Innovation and Digitization, CCCDI - Executive Agency for Higher Educa-tion, Research, Development & Innovation Funding (UEFISCDI) PN-III-P2-2.1-PTE-2021-0176
6 · The paper itself

Abstract

A growing body of evidence suggests that endometrial immune disorders may be responsible for endometrial dysfunctions that can lead to gynecological and obstetrical pathology. The aim of this study was to explore the potential relationship between different killer cell immunoglobulin-like receptor (KIR) genotypes and reproductive outcomes. We conducted a prospective cohort study that included 104 infertile patients undergoing an in vitro fertilization procedure. All participants underwent clinical and ultrasound examination, genetic evaluation (KIR genotyping), endometrial washing fluid sampling for cytokine determination, endometrial tissue sampling for histologic assessment and hysteroscopic evaluation. Our analysis showed statistically significant lower levels of uterine cytokines TNF-α (

Indexed as

endometrium disorderinfertilitykiller cell immunoglobulin-like receptor polymorphismNK cellsRomania

Identifiers

PMID37835791
PMCPMC10572162
OpenAlexW4387058956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.