ReviewDiagnostics (Basel, Switzerland)2023
Application of Multimodal MRI in the Early Diagnosis of Autism Spectrum Disorders: A Review.
Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- A bibliometric analysis of neuroimaging studies on cognitive control in autism spectrum disorder (2000-2025).Frontiers in psychiatry · 2026Pooled it
- Unveiling the glymphatic system's impact on neurodegenerative diseases: a comprehensive bibliometric analysis (2012-2024).Frontiers in aging neuroscience · 2025Pooled it
- Ceruloplasmin deficiency drives a fusiform-centric lipid-myelin pathology underlying a visual subtype in autism.Molecular psychiatry · 2026Article
- Factors linked to successful brain magnetic resonance imaging scans and data quality in autistic individuals across the functioning spectrum.BJPsych open · 2026Article
- MACAFNet transformer-based multi-atlas fusion framework for autism spectrum disorder classification using functional connectivity.Scientific reports · 2026Article
- Neuroimaging markers of cognition in late childhood associated with moderate to late preterm birth.Pediatric research · 2026Article
- Neurodevelopmental disorders in children: the role of MRI in early detection and intervention planning.Frontiers in neuroscience · 2026Review
- Post-Traumatic Stress Symptoms in Parents of Preschoolers First Diagnosed with Autism: Gender Differences and Correlations with Broad Autism Phenotypes.International journal of environmental research and public health · 2025Article
- The Effect of Prenatal Marijuana Exposure on White Matter Microstructure and Cortical Morphology during Late Childhood.AJNR. American journal of neuroradiology · 2025Article
- An Explainable Deep Learning Framework for Multimodal Autism Diagnosis Using XAI GAMI-Net and Hypernetworks.Diagnostics (Basel, Switzerland) · 2025Article
- GM-VGG-Net: A Gray Matter-Based Deep Learning Network for Autism Classification.Diagnostics (Basel, Switzerland) · 2025Article
- Combined deep and reinforcement learning with gaming to promote healthcare in neurodevelopmental disorders: a new hypothesis.Frontiers in human neuroscience · 2025Article
- Neuroimaging Correlates of the NIH-Toolbox-Driven Cognitive Metrics in Children.Journal of integrative neuroscience · 2024Article
- Treatment of Acute and Long-COVID, Diabetes, Myocardial Infarction, and Alzheimer's Disease: The Potential Role of a Novel Nano-Compound-The Transdermal Glutathione-Cyclodextrin Complex.Antioxidants (Basel, Switzerland) · 2024Review
- Innovative Strategies for Early Autism Diagnosis: Active Learning and Domain Adaptation Optimization.Diagnostics (Basel, Switzerland) · 2024Article
- Diagnosis for autism spectrum disorder children using T1-based gray matter and arterial spin labeling-based cerebral blood flow network metrics.Frontiers in neuroscience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Autism spectrum disorder (ASD) is a neurodevelopmental disorder in children. Early diagnosis and intervention can remodel the neural structure of the brain and improve quality of life but may be inaccurate if based solely on clinical symptoms and assessment scales. Therefore, we aimed to analyze multimodal magnetic resonance imaging (MRI) data from the existing literature and review the abnormal changes in brain structural-functional networks, perfusion, neuronal metabolism, and the glymphatic system in children with ASD, which could help in early diagnosis and precise intervention. Structural MRI revealed morphological differences, abnormal developmental trajectories, and network connectivity changes in the brain at different ages. Functional MRI revealed disruption of functional networks, abnormal perfusion, and neurovascular decoupling associated with core ASD symptoms. Proton magnetic resonance spectroscopy revealed abnormal changes in the neuronal metabolites during different periods. Decreased diffusion tensor imaging signals along the perivascular space index reflected impaired glymphatic system function in children with ASD. Differences in age, subtype, degree of brain damage, and remodeling in children with ASD led to heterogeneity in research results. Multimodal MRI is expected to further assist in early and accurate clinical diagnosis of ASD through deep learning combined with genomics and artificial intelligence.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.