Evidence map›Paper›PMID 37835686›Full record

ArticleAnimals : an open access journal from MDPI2023

Transmission Dynamics of Imported Vaccine-Origin PRRSV-2 within and between Commercial Swine Integrations in Hungary.

Szilvia Jakab, Krisztián Bányai, Krisztina Bali, Imre Nemes, Ádám Bálint, István Szabó

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Szilvia JakabHUN-REN Veterinary Medical Research Institute, Hungária krt. 21., H-1143 Budapest, Hungary.ORCID 0009-0005-8435-5507
Krisztián BányaiHUN-REN Veterinary Medical Research Institute, Hungária krt. 21., H-1143 Budapest, Hungary.
Krisztina BaliHUN-REN Veterinary Medical Research Institute, Hungária krt. 21., H-1143 Budapest, Hungary.ORCID 0000-0002-6906-0226
Imre NemesNational PRRS Eradication Committee, Keleti Károly utca. 24., H-1024 Budapest, Hungary.
Ádám BálintVeterinary Diagnostic Directorate, National Food Chain Safety Office, H-1143 Budapest, Hungary.
István SzabóNational PRRS Eradication Committee, Keleti Károly utca. 24., H-1024 Budapest, Hungary.ORCID 0000-0003-4786-8475

Funding

National Research, Development and Innovation Fund RRF- 2.3.1-21-2022-00001
6 · The paper itself

Abstract

This study reports on the molecular epidemiology of Ingelvac-PRRS-MLV-associated cases in Hungary for the period 2020-2021. Field epidemiology investigations led the experts to conclude that imported pigs, which were shipped through transit stations in Denmark, introduced the vaccine virus. The movement of fatteners and the neglect of disease control measures contributed to the spread of the virus to PRRS-free pig holdings in the vicinity. Deep sequencing was performed to genetically characterize the genes coding for the virion antigens (i.e., ORF2 through ORF7). The study isolates exhibited a range of 0.1 to 1.8% nucleotide sequence divergence from the Ingelvac PRRS MLV and identified numerous polymorphic sites (up to 57 sites) along the amplified 3.2 kilo base pair genomic region. Our findings confirm that some PRRSV-2 vaccine strains can accumulate very high number of point mutations within a short period in immunologically naive pig herds.

Indexed as

HungaryIngelvac PRRS MLVmolecular epidemiologyNA-type PRRSVnext-generation sequencingsingle nucleotide variationvirus transmission

Identifiers

PMID37835686
PMCPMC10571567

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.