Evidence map›Paper›PMID 37835596›Full record

ArticleCancers2023

Hashimoto's Thyroiditis and the Risk of Papillary Thyroid Cancer in Children.

Jean-Nicolas Gallant, Vivian L Weiss, Sheau-Chiann Chen, Jiancong Liang, Ryan H Belcher, Fei Ye, Hernan Correa, Huiying Wang

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Predictors of thyroid cancer in paediatric patients with thyroid nodules: A systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jean-Nicolas GallantDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0003-4696-2013
Vivian L WeissDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Sheau-Chiann ChenDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Jiancong LiangDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Ryan H BelcherDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0002-9490-3694
Fei YeDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Hernan CorreaDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Huiying WangDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Monroe Carell Jr. Children's Hospital · USVanderbilt University Medical Center · US

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
The Role of Cancer-Associated Fibroblasts in Thyroid CarcinomaR01CA272875 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEISS, VIVIAN LEE · 2022 to 2025
$2.5M
The role of Wnt signaling in aggressive thyroid carcinomaK08CA240901 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WEISS, VIVIAN LEE · 2020 to 2024
$1.1M
NCI NIH HHS K08 CA240901NCI NIH HHS K12 CA090625NCI NIH HHS R01 CA272875NIH HHS K08CA240901NIH HHS K12CA090625NIH HHS R01CA272875
6 · The paper itself

Abstract

The association between Hashimoto's thyroiditis (HT) and pediatric thyroid cancer is controversial. Most studies examining this connection have been based on adults, and larger studies in children are lacking. We performed a retrospective study of all sequential pediatric patients who underwent a thyroidectomy for a neoplasm at our institution over a twenty-year period in order to explore the link between HT and pediatric thyroid cancer. A total of 153 patients, median age 16.5 (interquartile range [IQR] 14.2-18.3) years, underwent thyroid surgery for a neoplasm. Patients were mainly female (80%) and White (84%). Median follow-up was 58.6 (IQR 20.7-105.4) months. Thirty-five (23%) patients had HT. Patients who underwent thyroid surgery and had HT were more likely to harbor a malignant neoplasm (

Indexed as

childrenHashimoto’s thyroiditispapillary thyroid carcinomapediatricthyroid cancerthyroid nodule

Identifiers

PMID37835596
PMCPMC10572053
OpenAlexW4387451782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.