Evidence map›Paper›PMID 37835564›Full record

ArticleCancers2023

A Network of 17 Microtubule-Related Genes Highlights Functional Deregulations in Breast Cancer.

Sylvie Rodrigues-Ferreira, Morgane Morin, Gwenn Guichaoua, Hadia Moindjie, Maria M Haykal, Olivier Collier, Véronique Stoven, Clara Nahmias

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Research progress of kinesin family in neurological diseases.Frontiers in cellular neuroscience · 2025
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sylvie Rodrigues-FerreiraGustave Roussy Cancer Center, F-94800 Villejuif, France.
Morgane MorinGustave Roussy Cancer Center, F-94800 Villejuif, France.
Gwenn GuichaouaCBIO (Centre de Bioinformatique), Mines Paris-PSL, PSL Research University, F-75005 Paris, France.ORCID 0009-0009-4225-4643
Hadia MoindjieGustave Roussy Cancer Center, F-94800 Villejuif, France.
Maria M HaykalGustave Roussy Cancer Center, F-94800 Villejuif, France.
Olivier CollierMODAL'X, UPL, Université Paris Nanterre, CNRS, F-92000 Nanterre, France.
Véronique StovenCBIO (Centre de Bioinformatique), Mines Paris-PSL, PSL Research University, F-75005 Paris, France.
Clara NahmiasGustave Roussy Cancer Center, F-94800 Villejuif, France.ORCID 0000-0001-6863-370X
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

Association PROLIFIC R20033LLCNRS, INSERM, Gustave Roussy 2023Fondation ARC PJA 20151203469Fondation pour la Recherche Médicale (FRM) 00119147/WB-2021-35655Fondation Rothschild 20222024Foundation JANSSEN HORIZON R19104LLFP2M Federation (CNRS FR 2036) ANR11-LBX-0023-01LERMIT HEALTHI Emergence 2000Ligue Nationale Contre le Cancer LNCC 2021ODYSSEA ATIP3Paris Ile de France DIM AI4IDFRuban Rose 23112022
6 · The paper itself

Abstract

A wide panel of microtubule-associated proteins and kinases is involved in coordinated regulation of the microtubule cytoskeleton and may thus represent valuable molecular markers contributing to major cellular pathways deregulated in cancer. We previously identified a panel of 17 microtubule-related (MT-Rel) genes that are differentially expressed in breast tumors showing resistance to taxane-based chemotherapy. In the present study, we evaluated the expression, prognostic value and functional impact of these genes in breast cancer. We show that 14 MT-Rel genes (

Indexed as

Aurora kinasesbiomarkerkinesinsmitotic defectsprognostic valueSystems Biologytherapeutic targets

Identifiers

PMID37835564
PMCPMC10571893
OpenAlexW4387458536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.