Evidence map›Paper›PMID 37835487›Full record

ArticleCancers2023

Differential Gene Expression of Checkpoint Markers and Cancer Markers in Mouse Models of Spontaneous Chronic Colitis.

Ramya Ephraim, Sarah Fraser, Jeannie Devereaux, Rhian Stavely, Jack Feehan, Rajaraman Eri, Kulmira Nurgali, Vasso Apostolopoulos

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Ramya EphraimInstitute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.
Sarah FraserInstitute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.
Jeannie DevereauxInstitute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.ORCID 0000-0003-3214-2938
Rhian StavelyPediatric Surgery Research Laboratories, Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-5099-3704
Jack FeehanInstitute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.ORCID 0000-0002-9627-1299
Rajaraman EriSTEM/School of Science, RMIT University, Melbourne, VIC 3001, Australia.
Kulmira NurgaliInstitute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.ORCID 0000-0002-2597-6929
Vasso ApostolopoulosInstitute for Health and Sport, Victoria University, Melbourne, VIC 3030, Australia.ORCID 0000-0001-6788-2771
Victoria University · AUAustralian Institute for Musculoskeletal Science · AUHarvard University · USRMIT University · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of checkpoint markers in cancer cells aids in immune escape. The identification of checkpoint markers and early cancer markers is of utmost importance to gain clarity regarding the relationship between colitis and progressive inflammation leading to cancer. Herein, the gene expression levels of checkpoint makers, cancer-related pathways, and cancer genes in colon tissues of mouse models of chronic colitis (

Indexed as

chronic colitiscolorectal cancerinflammationinflammatory bowel diseaseMuc2Muc2 missense mutationmucinWinnie mouse

Identifiers

PMID37835487
PMCPMC10571700
OpenAlexW4387169813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.