Evidence map›Paper›PMID 37835479›Full record

ArticleCancers2023

Alteration of the Exhaled Volatile Organic Compound Pattern in Colorectal Cancer Patients after Intentional Curative Surgery-A Prospective Pilot Study.

Julia Hanevelt, Ivonne J H Schoenaker, Richard M Brohet, Ruud W M Schrauwen, Frederique J N Baas, Pieter J Tanis, Henderik L van Westreenen, Wouter H de Vos Tot Nederveen Cappel

Registry-linked trialAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07620743 (Key Technology Research on Non-invasive Early Diagnosis of Colorectal Cancer Based on Odor-targeted Capture, Instant Detection, and Intelligent Analysis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07620743 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Key Technology Research on Non-invasive Early Diagnosis of Colorectal Cancer Based on Odor-targeted Capture, Instant Detection, and Intelligent Analysis

TypeobservationalSponsorBeijing University of Chinese MedicineRan2026 to 2029Enrolled453ConditionsCRC, Precancerous Condition, Healthy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Adaptive Machine Learning for Electronic Nose-Based Forensic VOC Classification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia HaneveltDepartment of Gastroenterology and Hepatology, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.ORCID 0000-0001-7418-9190
Ivonne J H SchoenakerIsala Oncology Center, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.ORCID 0000-0002-8628-8134
Richard M BrohetDepartment of Epidemiology and Statistics, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Ruud W M SchrauwenDepartment of Gastroenterology and Hepatology, Bernhoven, Nistelrodeseweg 10, 5406 PT Uden, The Netherlands.
Frederique J N BaasDepartment of Gastroenterology and Hepatology, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.
Pieter J TanisDepartment of Surgery, University Medical Center Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Henderik L van WestreenenDepartment of Surgery, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.ORCID 0000-0002-1910-2723
Wouter H de Vos Tot Nederveen CappelDepartment of Gastroenterology and Hepatology, Isala, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands.

Funding

The eNose (Netherlands) not indicated
6 · The paper itself

Abstract

As current follow-up modalities for colorectal carcinoma (CRC) have restricted sensitivity, novel diagnostic tools are needed. The presence of CRC changes the endogenous metabolism, resulting in the release of a specific volatile organic compounds (VOC) pattern that can be detected with an electronic nose or Aeonose

Indexed as

AeonoseTMcolorectal cancerelectronic noseVOCsvolatile organic compounds

Identifiers

PMID37835479
PMCPMC10571749

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.