Evidence map›Paper›PMID 37835448›Full record

ArticleCancers2023

Changes in Sexuality and Sexual Dysfunction over Time in the First Two Years after Treatment of Head and Neck Cancer.

Margot A Stone, Birgit I Lissenberg-Witte, Remco de Bree, Jose A Hardillo, Femke Lamers, Johannes A Langendijk, C René Leemans, Robert P Takes, Femke Jansen, Irma M Verdonck-de Leeuw

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Margot A StoneDepartment Otolaryngology-Head and Neck Surgery, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
Birgit I Lissenberg-WitteCancer Center Amsterdam, Treatment and Quality of Life, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-9448-1826
Remco de BreeDepartment of Head and Neck Surgical Oncology, University Medical Center Utrecht, 3584 CS Utrecht, The Netherlands.ORCID 0000-0001-7128-5814
Jose A HardilloDepartment of Otorhinolaryngology, Erasmus MC, University Medical Center, 3000 CA Rotterdam, The Netherlands.ORCID 0000-0001-5580-5613
Femke LamersDepartment of Psychiatry, Amsterdam UMC, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0003-4344-5766
Johannes A LangendijkDepartment of Radiation Oncology, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0003-1083-372X
C René LeemansDepartment Otolaryngology-Head and Neck Surgery, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0001-7887-083X
Robert P TakesDepartment of Otorhinolaryngology-Head and Neck Surgery, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Femke JansenDepartment Otolaryngology-Head and Neck Surgery, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
Irma M Verdonck-de LeeuwDepartment Otolaryngology-Head and Neck Surgery, Amsterdam UMC, Vrije Universiteit Amsterdam, 1081 HV Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLErasmus MC · NLRadboud University Nijmegen · NLUniversity Medical Center Groningen · NLUniversity Medical Center Utrecht · NL

Funding

Dutch Cancer Society VU 2013-5930
6 · The paper itself

Abstract

The aim of this study was to investigate changes in sexuality and sexual dysfunction in head and neck cancer (HNC) patients in the first two years after treatment, in relation to the type of treatment. Data were used of 588 HNC patients participating in the prospective NETherlands Quality of life and Biomedical Cohort Study (NET-QUBIC) from diagnosis to 3, 6, 12 and 24 months after treatment. Primary outcome measures were the International Index of Erectile Function (IIEF) and the Female Sexual Function Index (FSFI). The total scores of the IIEF and FSFI were dichotomized into sexual (dys)function. In men, type of treatment was significantly associated with change in erectile function, orgasm, satisfaction with intercourse, and overall satisfaction. In women, type of treatment was significantly associated with change in desire, arousal, and orgasm. There were significant differences between treatment groups in change in dysfunctional sexuality. A deterioration in sexuality and sexual dysfunction from baseline to 3 months after treatment was observed especially in patients treated with chemoradiation. Changes in sexuality and sexual dysfunction in HNC patients were related to treatment, with an acute negative effect of chemoradiation. This effect on the various domains of sexuality seems to differ between men and women.

Indexed as

chemotherapyhead and neck cancerradiotherapysexual dysfunctionsexualitysurgery

Identifiers

PMID37835448
PMCPMC10571543
OpenAlexW4387121002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.