Evidence map›Paper›PMID 37835359›Full record

ReviewFoods (Basel, Switzerland)2023

An Update on the Pivotal Roles of Probiotics, Their Components, and Metabolites in Preventing Colon Cancer.

Xue Deng, Jing Yang, Yu Zhang, Xiaoyong Chen, Chen Wang, Huayi Suo, Jiajia Song

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Molecular Mechanisms of Probiotic Action Against Gastrointestinal Cancers.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
  8. Microbiology spectrum · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Effects of Viable and Heat-InactivatedFoods (Basel, Switzerland) · 2024
    Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xue DengCollege of Food Science, Southwest University, Chongqing 400715, China.
Jing YangChongqing Engineering Research Center for Processing & Storage of Distinct Agricultural Products, Chongqing Technology and Business University, Chongqing 400067, China.ORCID 0000-0002-1352-225X
Yu ZhangCollege of Food Science, Southwest University, Chongqing 400715, China.
Xiaoyong ChenCollege of Food Science, Southwest University, Chongqing 400715, China.
Chen WangCollege of Food Science, Southwest University, Chongqing 400715, China.
Huayi SuoCollege of Food Science, Southwest University, Chongqing 400715, China.ORCID 0000-0003-0024-231X
Jiajia SongCollege of Food Science, Southwest University, Chongqing 400715, China.ORCID 0000-0001-6753-518X
Southwest University · CNChongqing Technology and Business University · CN

Funding

Commission Major Science and Technology Special Projects in Tibet Autonomous Region XZ202201ZD0001NKey Construction Disciplines of Traditional Chinese Medicine in Chongqing 2021-4322190044Natural Science Foundation of Chongqing cstc2021jcyj-msxmX0772Science and Technology Research Program of Chongqing Municipal Education KJQN202300204University Innovation Research Group in Chongqing CXQT21007
6 · The paper itself

Abstract

Diet, lifestyle, and gut microbiota composition are key risk factors for the progression of colon cancer. Probiotics are living microorganisms that can offer health benefits to the parasitifer when ingested in competent quantities. Several in vivo, in vitro, and clinical studies have demonstrated that probiotics can prevent and mitigate the development of colon cancer. The anti-colon cancer mechanisms of probiotics include the suppression of cell proliferation and the promotion of cancer cell apoptosis, immunomodulation, the modulation of intestinal microorganisms and their metabolism, strengthening the intestinal barrier, and antioxidant effects. This article describes the pathogenesis of colon cancer and the available therapeutic options. In addition, this paper reviews the mechanisms by which probiotics mitigate colon cancer as well as the mitigating effects of probiotic components and metabolites on colon cancer.

Indexed as

anti-cancer mechanismscolon cancercolon cancer treatmentprobiotics

Identifiers

PMID37835359
PMCPMC10572180
OpenAlexW4387460173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.