Evidence map›Paper›PMID 37834972›Full record

ArticleJournal of clinical medicine2023

Comparison of Maternal and Neonatal Outcomes between SARS-CoV-2 Variants: A Retrospective, Monocentric Study.

Giosuè Giordano Incognito, Rosario Emanuele Carlo Distefano, Giorgia Campo, Ferdinando Antonio Gulino, Chiara Gulisano, Chiara Gullotta, Giuseppe Gullo, Gaspare Cucinella, Attilio Tuscano, Maria Teresa Bruno and 1 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Giosuè Giordano IncognitoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95100 Catania, Italy.ORCID 0000-0002-1818-0105
Rosario Emanuele Carlo DistefanoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95100 Catania, Italy.ORCID 0000-0003-2512-8492
Giorgia CampoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95100 Catania, Italy.
Ferdinando Antonio GulinoUnit of Gynecology and Obstetrics, Department of Human Pathology of Adults and Developmental Age, University Hospital "G. Martino", 98100 Messina, Italy.
Chiara GulisanoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95100 Catania, Italy.
Chiara GullottaDepartment of Clinical and Experimental Medicine, University of Messina, 98100 Messina, Italy.
Giuseppe GulloAzienda Ospedaliera Ospedali Riuniti (AOOR) Villa Sofia Cervello, University of Palermo, 90133 Palermo, Italy.ORCID 0000-0003-4269-4269
Gaspare CucinellaAzienda Ospedaliera Ospedali Riuniti (AOOR) Villa Sofia Cervello, University of Palermo, 90133 Palermo, Italy.
Attilio TuscanoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95100 Catania, Italy.
Maria Teresa BrunoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95100 Catania, Italy.ORCID 0000-0003-1557-1538
Marco PalumboDepartment of General Surgery and Medical Surgical Specialties, University of Catania, 95100 Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of SARS-CoV-2 variants on maternal and neonatal outcomes during pregnancy is still poorly understood, and the emergence of different variants has further complicated our understanding of the virus's effects. This retrospective, monocentric study aimed to fill this knowledge gap by analyzing the outcomes of pregnant women with acute SARS-CoV-2 infection caused by the Alpha, Delta, and Omicron variants. The study, conducted between December 2020 and March 2022 at San Marco Hospital, included 313 pregnant women with confirmed SARS-CoV-2 infection. The results showed that the Delta variant was associated with a significantly higher incidence of adverse outcomes, such as premature births, maternal intensive care unit admission, intrauterine growth restriction, and small for gestational age infants. Additionally, the Delta variant was linked to lower Apgar scores, higher maternal and fetal mortality rates, and increased levels of various biomarkers indicating more severe illness. Finally, the Delta variant also presented a greater possibility of vertical transmission. These findings underscore the complexity of understanding the impact of SARS-CoV-2 on pregnancy outcomes, especially considering the distinctive characteristics of different variants. By better understanding the specific impacts of each variant, appropriate preventive measures and management strategies can be implemented to optimize maternal and neonatal outcomes.

Indexed as

COVID-19infectionmaternal outcomesneonatal outcomesSARS-CoV-2

Identifiers

PMID37834972
PMCPMC10573122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.