Evidence map›Paper›PMID 37834931›Full record

ArticleJournal of clinical medicine2023

Patterns of Cough Medication Prescribing among Patients with Chronic Cough in Florida: 2012-2021.

Seonkyeong Yang, Shu Huang, Juan M Hincapie-Castillo, Xuehua Ke, Helen Ding, Jonathan Schelfhout, Mandel R Sher, Bobby Jones, Debbie L Wilson, Wei-Hsuan Lo-Ciganic

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Seonkyeong YangDepartment of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-5198-8544
Shu HuangDepartment of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-2825-9180
Juan M Hincapie-CastilloDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.ORCID 0000-0002-6945-2713
Xuehua KeCenter for Observational and Real-World Evidence (CORE), Merck & Co., Inc., Rahway, NJ 07065, USA.
Helen DingCenter for Observational and Real-World Evidence (CORE), Merck & Co., Inc., Rahway, NJ 07065, USA.
Jonathan SchelfhoutCenter for Observational and Real-World Evidence (CORE), Merck & Co., Inc., Rahway, NJ 07065, USA.
Mandel R SherCenter for Cough, Largo, FL 33778, USA.
Bobby JonesDepartment of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.
Debbie L WilsonDepartment of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0002-1640-5497
Wei-Hsuan Lo-CiganicDepartment of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0001-6590-4770
University of Florida · USMerck & Co., Inc., Rahway, NJ, USA (United States) · USCenter for Drug Evaluation and Research · USFlorida Center for Gastroenterology · USUniversity of North Carolina at Chapel Hill · US

Funding

Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA. C2116 (NIS008067)
6 · The paper itself

Abstract

Among patients with chronic cough (CC) in the 2012-2021 statewide OneFlorida Clinical Research Consortium database, we examined trends in cough medication (CM) prescribing prevalence over time in repeated cross-sectional analyses and identified distinct CM utilization trajectories using group-based trajectory modeling (GBTM) in a retrospective cohort study. Among eligible adults (≥18 years) without cancer/benign respiratory tumor diagnoses, we identified CC patients and non-CC patients with any cough-related diagnosis. In the GBTM analysis, we calculated the number of monthly prescriptions for any CMs (excluding gabapentinoids) during the 12 months from the first qualifying cough event to identify distinct utilization trajectories. From 2012 to 2021, benzonatate (9.6% to 26.1%), dextromethorphan (5.2% to 8.6%), and gabapentinoid (5.3% to 14.4%) use increased among CC patients, while opioid antitussive use increased from 2012 to 2015 and decreased thereafter (8.4% in 2012, 14.7% in 2015, 6.7% in 2021; all

Indexed as

antitussivebenzonatatechronic coughcoughcough hypersensitivity syndromedextromethorphandrug utilizationgabapentinoidgroup-based trajectory modelingopioid antitussive

Identifiers

PMID37834931
PMCPMC10573590
OpenAlexW4387186908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.