Evidence map›Paper›PMID 37834907›Full record

ArticleJournal of clinical medicine2023

Hospital Admission Factors Independently Affecting the Risk of Mortality of COVID-19 Patients.

Marcin Paciorek, Carlo Bieńkowski, Justyna Dominika Kowalska, Agata Skrzat-Klapaczyńska, Agnieszka Bednarska, Dominika Krogulec, Grażyna Cholewińska, Jacek Kowalski, Regina Podlasin, Katarzyna Ropelewska-Łącka and 6 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Marcin PaciorekDepartment of Adults' Infectious Diseases, Medical University of Warsaw, 02-001 Warsaw, Poland.ORCID 0000-0002-1757-1999
Carlo BieńkowskiDepartment of Adults' Infectious Diseases, Medical University of Warsaw, 02-001 Warsaw, Poland.ORCID 0000-0002-6488-4576
Justyna Dominika KowalskaDepartment of Adults' Infectious Diseases, Medical University of Warsaw, 02-001 Warsaw, Poland.ORCID 0000-0003-1166-4462
Agata Skrzat-KlapaczyńskaDepartment of Adults' Infectious Diseases, Medical University of Warsaw, 02-001 Warsaw, Poland.ORCID 0000-0002-6367-5633
Agnieszka BednarskaDepartment of Adults' Infectious Diseases, Medical University of Warsaw, 02-001 Warsaw, Poland.
Dominika KrogulecDepartment of Adults' Infectious Diseases, Medical University of Warsaw, 02-001 Warsaw, Poland.
Grażyna CholewińskaHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, Poland.
Jacek KowalskiHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, Poland.
Regina PodlasinHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, Poland.ORCID 0000-0002-4063-1646
Katarzyna Ropelewska-ŁąckaHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, Poland.
Piotr WasilewskiHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, Poland.ORCID 0000-0001-9301-7140
Piotr W BorosLung Pathophysiology Department, National TB & Lung Diseases Research Institute, 01-138 Warsaw, Poland.ORCID 0000-0002-9153-8919
Magdalena M Martusiewicz-Boros3rd Lung Diseases & Oncology Department, National TB & Lung Diseases Research Institute, 01-138 Warsaw, Poland.ORCID 0000-0002-7027-757X
Piotr PulikHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, Poland.
Andrzej PihowiczHospital for Infectious Diseases in Warsaw, 01-201 Warsaw, Poland.
Andrzej HorbanDepartment of Adults' Infectious Diseases, Medical University of Warsaw, 02-001 Warsaw, Poland.

Funding

Medical Research Agency 2020/ABM/COVID-19/0077
6 · The paper itself

Abstract

introductionCOVID-19 is a disease characterized by high in-hospital mortality, which seems to be dependent on many predisposing factors.

objectivesThe aim of this study was to analyze the clinical symptoms, abnormalities in the results of laboratory tests, and coexisting chronic diseases that independently affected the risk of in-hospital mortality in patients with COVID-19. PATIENTS AND

methodsWe analyzed the records of patients with COVID-19 who were hospitalized from 6 March 2020 to 30 November 2021.

resultsOut of the entire group of 2138 patients who were analyzed, 12.82% died during hospitalization. In-hospital mortality was independently associated with older age (OR 1.53, 95% CI 1.20-1.97); lower arterial blood oxygen saturation (OR 0.95, 95% CI 0.92-0.99); the presence of a neoplasm (OR 4.45, 95% CI 2.01-9.62), a stomach ulcer (OR 3.35, 95% CI 0.94-11.31), and dementia (OR 3.40, 95% CI 1.36-8.26); a higher score on the SOFA scale (OR 1.73, 95% CI 1.52-1.99); higher lactate dehydrogenase (LDH) (OR 1.08, 95% CI 1.05-1.12); higher N-terminal pro-brain natriuretic peptide (NT pro BNP) (OR 1.06, 95% CI 1.01-1.11); and lower total bilirubin in blood concentration (OR 0.94, 95% CI 0.90-0.99).

conclusionsWe found that low oxygen saturation, old age, and the coexistence of cancer, gastric ulcers, and dementia syndrome were variables that independently increased mortality during hospitalization due to COVID-19. Moreover, we found that decreased platelet count and bilirubin concentration and increased levels of LDH and NT-proBNP were laboratory test results that independently indicated a higher risk of mortality. We also confirmed the usefulness of the SOFA scale in predicting treatment results. The ability to identify mortality risk factors on admission to hospital will facilitate both adjusting the intensity of treatment and the monitoring of patients infected with SARS-CoV-2.

Indexed as

COVID-19mortalityrisk factorsSARS-CoV-2

Identifiers

PMID37834907
PMCPMC10573469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.