Evidence map›Paper›PMID 37834396›Full record

ArticleInternational journal of molecular sciences2023

Enhancing Giardicidal Activity and Aqueous Solubility through the Development of "RetroABZ", a Regioisomer of Albendazole: In Vitro, In Vivo, and In Silico Studies.

Carlos Martínez-Conde, Blanca Colín-Lozano, Abraham Gutiérrez-Hernández, Emanuel Hernández-Núñez, Lilián Yépez-Mulia, Luis Fernando Colorado-Pablo, Rodrigo Aguayo-Ortiz, Jaime Escalante, Julio C Rivera-Leyva, Jessica Nayelli Sánchez-Carranza and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Carlos Martínez-CondeFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico.
Blanca Colín-LozanoFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico.
Abraham Gutiérrez-HernándezFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico.
Emanuel Hernández-NúñezDepartamento de Recursos del Mar, Centro de Investigación y de Estudios Avanzados, IPN, Unidad Mérida, Merida 97310, Yucatán, Mexico.
Lilián Yépez-MuliaUnidad de Investigación Medica en Enfermedades Infecciosas y Parasitarias, Unidad Médica de Alta Especialidad-Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City 06720, Mexico.ORCID 0000-0001-8675-5671
Luis Fernando Colorado-PabloDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de Mexico, Mexico City 04510, Mexico.
Rodrigo Aguayo-OrtizDepartamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de Mexico, Mexico City 04510, Mexico.ORCID 0000-0001-9455-5397
Jaime EscalanteCentro de Investigaciones Químicas-IICBA, Universidad Autónoma del Estado de Morelos, Av. Universidad 1001, Cuernavaca 62209, Morelos, Mexico.ORCID 0000-0001-5485-0244
Julio C Rivera-LeyvaFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico.ORCID 0000-0002-5521-1791
Jessica Nayelli Sánchez-CarranzaFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico.
Elizabeth Barbosa-CabreraSección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, IPN, Mexico City 11340, Mexico.ORCID 0000-0002-7111-7922
Gabriel Navarrete-VazquezFacultad de Farmacia, Universidad Autónoma del Estado de Morelos, Cuernavaca 62209, Morelos, Mexico.ORCID 0000-0001-5344-4762
Universidad Autónoma del Estado de Morelos · MXInstituto Politécnico Nacional · MXUniversidad Nacional Autónoma de México · MXMexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parasitic diseases, including giardiasis caused by

Indexed as

Antiprotozoal AgentsGiardia lambliaGiardiasisAlbendazoleAnimalsMiceMolecular Docking SimulationSolubilityTubulinAlbendazoleAntiprotozoal AgentsTubulinalbendazolebenzimidazoledockinggiardicidalsolubility

Identifiers

PMID37834396
PMCPMC10573946
OpenAlexW4387401295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.