Evidence map›Paper›PMID 37834380›Full record

ReviewInternational journal of molecular sciences2023

MRI and Clinical Biomarkers Overlap between Glaucoma and Alzheimer's Disease.

Alessio Martucci, Francesca Di Giuliano, Silvia Minosse, Giulio Pocobelli, Carlo Nucci, Francesco Garaci

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. [Research progress on the mechanism of auditory center remodeling and clinical intervention strategies in presbycusis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Review
  4. Review
  5. Review
  6. Retinal vascular dysfunction in the MthfrAlzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Basic, Translational, and Clinical Research on Dementia.International journal of molecular sciences · 2024
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alessio MartucciOphthalmology Unit, Department of Experimental Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-3725-8211
Francesca Di GiulianoNeuroradiology Unit, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-6067-183X
Silvia MinosseDiagnostic Imaging Unit, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
Giulio PocobelliOphthalmology Unit, Department of Experimental Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Carlo NucciOphthalmology Unit, Department of Experimental Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Francesco GaraciDiagnostic Imaging Unit, Department of Biomedicine and Prevention, University of Rome "Tor Vergata", 00133 Rome, Italy.
University of Rome Tor Vergata · IT

Funding

MNESYS study PE00000006 CUP:E83C22004710001
6 · The paper itself

Abstract

Glaucoma is the leading cause of blindness worldwide. It is classically associated with structural and functional changes in the optic nerve head and retinal nerve fiber layer, but the damage is not limited to the eye. The involvement of the central visual pathways and disruption of brain network organization have been reported using advanced neuroimaging techniques. The brain structural changes at the level of the areas implied in processing visual information could justify the discrepancy between signs and symptoms and underlie the analogy of this disease with neurodegenerative dementias, such as Alzheimer's disease, and with the complex group of pathologies commonly referred to as "disconnection syndromes." This review aims to summarize the current state of the art on the use of advanced neuroimaging techniques in glaucoma and Alzheimer's disease, highlighting the emerging biomarkers shared by both diseases.

Indexed as

Alzheimer DiseaseGlaucomaBiomarkersBrainHumansMagnetic Resonance ImagingNeuroimagingBiomarkersAlzheimer’s diseaseclinical biomarkersdiffusion magnetic resonancefunctional magnetic resonanceglaucomamagnetic resonance imagingneuroimaging

Identifiers

PMID37834380
PMCPMC10573932
OpenAlexW4387404485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.