Evidence map›Paper›PMID 37834284›Full record

ReviewInternational journal of molecular sciences2023

Tumor Cell Resistance to the Inhibition of BRAF and MEK1/2.

Wenjing Chen, Jong-In Park

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Multilevel Mechanisms of Cancer Drug Resistance.International journal of molecular sciences · 2024
    Pooled it
  2. Review
  3. Article
  4. Variable thresholds for phosphorylation targets of the ERK signaling pathway.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Dual targeting of BRAFJournal of experimental & clinical cancer research : CR · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Special Issue: MAPK Signaling Cascades in Human Health and Diseases.International journal of molecular sciences · 2024
    Article
  14. Cells · 2024
    Article
  15. Targeting MEK in non-small cell lung cancer.Current problems in cancer · 2024
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wenjing ChenDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Jong-In ParkDepartment of Biochemistry, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0001-7248-4735
Medical College of Wisconsin · US

Funding

Mechanisms of MEK/ERK growth arrest signalingR01CA138441 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI PARK, JONG-IN · 2010 to 2020
$2.9M
The Role of Mortalin in Thyroid CancerR01CA269452 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Jong-In Park · 2023 to 2026
$1.7M
NCI NIH HHS R01 CA138441NCI NIH HHS R01CA138441NCI NIH HHS R01 CA269452NCI NIH HHS R01CA269452
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Protein Kinase InhibitorsProto-Oncogene Proteins B-rafCell Line, TumorDrug Resistance, NeoplasmMAP Kinase Kinase 1MutationSignal TransductionMAP Kinase Kinase 1Protein Kinase InhibitorsProto-Oncogene Proteins B-rafBRAFdrug resistanceMEKtumor

Identifiers

PMID37834284
PMCPMC10573597
OpenAlexW4387266478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.