Evidence map›Paper›PMID 37834211›Full record

ArticleInternational journal of molecular sciences2023

Mitochondrial Metabolism in the Spotlight: Maintaining Balanced RNAP III Activity Ensures Cellular Homeostasis.

Roza Szatkowska, Emil Furmanek, Andrzej M Kierzek, Christian Ludwig, Malgorzata Adamczyk

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Roza SzatkowskaLaboratory of Systems and Synthetic Biology, Chair of Drugs and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland.
Emil FurmanekLaboratory of Systems and Synthetic Biology, Chair of Drugs and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland.
Andrzej M KierzekCertara UK Limited, Sheffield S1 2BJ, UK.
Christian LudwigInstitute of Metabolism and Systems Research, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0001-8901-6970
Malgorzata AdamczykLaboratory of Systems and Synthetic Biology, Chair of Drugs and Cosmetics Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland.ORCID 0000-0003-3979-0364
Warsaw University of Technology · PLUniversity of Birmingham · GBUniversity of Surrey · GB

Funding

EMBO 6069Faculty of Chemistry Warsaw University of Technology Nchem2 no. 504/04632/1020/43.120010Faculty of Chemistry Warsaw University of Technology Nchem2 no.504/04632/1020/43.120012National Science Center 2012/05/E/NZ2/00583
6 · The paper itself

Abstract

RNA polymerase III (RNAP III) holoenzyme activity and the processing of its products have been linked to several metabolic dysfunctions in lower and higher eukaryotes. Alterations in the activity of RNAP III-driven synthesis of non-coding RNA cause extensive changes in glucose metabolism. Increased RNAP III activity in the

Indexed as

MitochondriaSaccharomyces cerevisiaeHomeostasisRNA, TransferRNA, UntranslatedRNA, TransferRNA, Untranslated13C fluxgrowth rateMAF1mitochondrial metabolismRNAP IIIRNA polymerase IIIsystems biologyTCA cycle

Identifiers

PMID37834211
PMCPMC10572830
OpenAlexW4387231079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.