Evidence map›Paper›PMID 37834167›Full record

ArticleInternational journal of molecular sciences2023

Perspectives on Scaffold Designs with Roles in Liver Cell Asymmetry and Medical and Industrial Applications by Using a New Type of Specialized 3D Bioprinter.

Iuliana Harbuz, Daniel Dumitru Banciu, Rodica David, Cristina Cercel, Octavian Cotîrță, Bogdan Marius Ciurea, Sorin Mihai Radu, Stela Dinescu, Sorin Ion Jinga, Adela Banciu

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In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Iuliana HarbuzDepartment of Biomaterials and Medical Devices, Faculty of Medical Engineering, Politehnica University of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Daniel Dumitru BanciuDepartment of Biomaterials and Medical Devices, Faculty of Medical Engineering, Politehnica University of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Rodica DavidInstitute for Research on the Quality of Society and the Sciences of Education, University Constantin Brancusi of Targu Jiu, Republicii 1, 210185 Targu Jiu, Romania.
Cristina CercelUniversity of Medicine and Pharmacy "Carol Davila" Bucharest, 37 Dionisie Lupu Street, 020021 Bucharest, Romania.
Octavian CotîrțăDepartment of Biomaterials and Medical Devices, Faculty of Medical Engineering, Politehnica University of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Bogdan Marius CiureaDepartment of Biomaterials and Medical Devices, Faculty of Medical Engineering, Politehnica University of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Sorin Mihai RaduDepartment of Mechanical Industrial and Transportation Engineering, University of Petrosani, 332006 Petrosani, Romania.
Stela DinescuDepartment of Mechanical Industrial and Transportation Engineering, University of Petrosani, 332006 Petrosani, Romania.ORCID 0000-0003-0277-7481
Sorin Ion JingaDepartment of Biomaterials and Medical Devices, Faculty of Medical Engineering, Politehnica University of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Adela BanciuDepartment of Biomaterials and Medical Devices, Faculty of Medical Engineering, Politehnica University of Bucharest, 1-7 Gh. Polizu Street, 011061 Bucharest, Romania.
Universitatea Națională de Știință și Tehnologie Politehnica București · ROUniversitatea Din Petrosani · ROCarol Davila University of Medicine and Pharmacy · ROConstantin Brâncuși University of Targu Jiu · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular asymmetry is an important element of efficiency in the compartmentalization of intracellular chemical reactions that ensure efficient tissue function. Improving the current 3D printing methods by using cellular asymmetry is essential in producing complex tissues and organs such as the liver. The use of cell spots containing at least two cells and basement membrane-like bio support materials allows cells to be tethered at two points on the basement membrane and with another cell in order to maintain cell asymmetry. Our model is a new type of 3D bioprinter that uses oriented multicellular complexes with cellular asymmetry. This novel approach is necessary to replace the sequential and slow processes of organogenesis with rapid methods of growth and 3D organ printing. The use of the extracellular matrix in the process of bioprinting with cells allows one to preserve the cellular asymmetry in the 3D printing process and thus preserve the compartmentalization of biological processes and metabolic efficiency.

Indexed as

BioprintingTissue ScaffoldsHepatocytesLiverPrinting, Three-DimensionalTissue Engineering3D printingcellular asymmetryscaffold

Identifiers

PMID37834167
PMCPMC10573170
OpenAlexW4387170754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.