Evidence map›Paper›PMID 37834151›Full record

ArticleInternational journal of molecular sciences2023

Electrophoretic Determination of L-Carnosine in Health Supplements Using an Integrated Lab-on-a-Chip Platform with Contactless Conductivity Detection.

Iva Pukleš, Csilla Páger, Nikola Sakač, Bojan Šarkanj, Brunislav Matasović, Mirela Samardžić, Mateja Budetić, Dean Marković, Marija Jozanović

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Iva PuklešDepartment of Chemistry, Josip Juraj Strossmayer University of Osijek, Cara Hadrijana 8, 31000 Osijek, Croatia.
Csilla PágerInstitute of Bioanalysis, Medical School, Szentágothai Research Center, University of Pécs, Honvéd Utca 1, 7624 Pécs, Hungary.ORCID 0000-0002-0031-059X
Nikola SakačFaculty of Geotechnical Engineering, University of Zagreb, Hallerova 7, 42000 Varaždin, Croatia.
Bojan ŠarkanjDepartment of Food Technology, University North, Trg dr. Žarka Dolinara 1, 48000 Koprivnica, Croatia.ORCID 0000-0002-1567-6455
Brunislav MatasovićDepartment of Chemistry, Josip Juraj Strossmayer University of Osijek, Cara Hadrijana 8, 31000 Osijek, Croatia.ORCID 0000-0002-5727-0613
Mirela SamardžićDepartment of Chemistry, Josip Juraj Strossmayer University of Osijek, Cara Hadrijana 8, 31000 Osijek, Croatia.
Mateja BudetićDepartment of Chemistry, Josip Juraj Strossmayer University of Osijek, Cara Hadrijana 8, 31000 Osijek, Croatia.
Dean MarkovićDepartment of Biotechnology, University of Rijeka, Radmile Matejčić 2, 51000 Rijeka, Croatia.ORCID 0000-0002-6218-973X
Marija JozanovićDepartment of Chemistry, Josip Juraj Strossmayer University of Osijek, Cara Hadrijana 8, 31000 Osijek, Croatia.ORCID 0000-0002-9509-8105

Funding

European Structural and Investment Funds grant for the Croatian National Scientific Center of Excellence for Personalized Health Care, Josip Juraj Strossmayer University of Osijek #KK.01.1.1.01.0010
6 · The paper itself

Abstract

The health supplement industry is one of the fastest growing industries in the world, but there is a lack of suitable analytical methods for the determination of active compounds in health supplements such as peptides. The present work describes an implementation of contactless conductivity detection on microchip technology as a new strategy for the electrophoretic determination of L-carnosine in complex health supplement formulations without pre-concentration and derivatization steps. The best results were obtained in the case of +1.00 kV applied for 20 s for injection and +2.75 kV applied for 260 s for the separation step. Under the selected conditions, a linear detector response of 5 × 10

Indexed as

CarnosineElectrophoresis, MicrochipElectric ConductivityInjectionsLab-On-A-Chip DevicesReproducibility of ResultsCarnosinecapacitively coupled contactless conductivity detectiongreen analytical chemistrylab-on-a-chipL-carnosinemicrochip electrophoresis

Identifiers

PMID37834151
PMCPMC10572305

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.