Evidence map›Paper›PMID 37834109›Full record

ArticleInternational journal of molecular sciences2023

Anhydrous Alum Inhibits α-MSH-Induced Melanogenesis by Down-Regulating MITF via Dual Modulation of CREB and ERK.

Kyu-Ree In, Mi Ae Kang, Su Dong Kim, Jinho Shin, Sung Un Kang, Tae Jun Park, Seung-Joo Kim, Jong-Soo Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kyu-Ree InDepartment of Life Sciences, College of Natural Sciences, Ajou University, Suwon 16499, Republic of Korea.
Mi Ae KangDepartment of Life Sciences, College of Natural Sciences, Ajou University, Suwon 16499, Republic of Korea.ORCID 0000-0002-2353-3892
Su Dong KimGraduate School of Clinical Pharmacy and Pharmaceutics, Ajou University, Suwon 16499, Republic of Korea.
Jinho ShinDepartment of Chemistry, College of Natural Sciences, Ajou University, Suwon 16499, Republic of Korea.
Sung Un KangDepartment of Otolaryngology, School of Medicine, Ajou University, Suwon 16499, Republic of Korea.
Tae Jun ParkDepartment of Biomedical Science, The Graduate School, Ajou University, Suwon 16499, Republic of Korea.
Seung-Joo KimResearch Institute of Basic Sciences, Ajou University, Suwon 16499, Republic of Korea.ORCID 0000-0002-9945-5181
Jong-Soo LeeDepartment of Life Sciences, College of Natural Sciences, Ajou University, Suwon 16499, Republic of Korea.ORCID 0000-0001-9226-3390
Ajou University · KR

Funding

Ministry of Education NRF-2021R1A6A1A10044950, 2020R1A2C201130214
6 · The paper itself

Abstract

Melanogenesis, the intricate process of melanin synthesis, is central to skin pigmentation and photoprotection and is regulated by various signaling pathways and transcription factors. To develop potential skin-whitening agents, we used B16F1 melanoma cells to investigate the inhibitory effects of anhydrous alum on melanogenesis and its underlying molecular mechanisms. Anhydrous alum (KAl(SO

Indexed as

alpha-MSHMelaninsAlum CompoundsCell Line, TumorMicrophthalmia-Associated Transcription FactorMonophenol Monooxygenasealpha-MSHAlum Compoundsaluminum sulfateMelaninsMicrophthalmia-Associated Transcription FactorMonophenol Monooxygenaseanhydrous alumCREBERKmelanogenesisMITF

Identifiers

PMID37834109
PMCPMC10572554
OpenAlexW4387137803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.