Evidence map›Paper›PMID 37834097›Full record

ArticleInternational journal of molecular sciences2023

Immunohistochemical Expression of Glutathione Peroxidase-2 (Gpx-2) and Its Clinical Relevance in Colon Adenocarcinoma Patients.

Marlena Brzozowa-Zasada, Angela Ianaro, Adam Piecuch, Marek Michalski, Natalia Matysiak, Katarzyna Stęplewska

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Study on the molecular aspect of cardioprotective effects of selenium: a mini-review.Journal of basic and clinical physiology and pharmacology · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Glutathione-Dependent Pathways in Cancer Cells.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Article
  13. A Prognostic Activity of Glutaredoxin 1 Protein (Grx1) in Colon Cancer.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Marlena Brzozowa-ZasadaDepartment of Histology and Cell Pathology in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0002-9363-3872
Angela IanaroDepartment of Pharmacy, School of Medicine, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0003-2520-9647
Adam PiecuchDepartment of Histology and Cell Pathology in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Marek MichalskiDepartment of Histology and Cell Pathology in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.ORCID 0000-0003-2045-7211
Natalia MatysiakDepartment of Histology and Cell Pathology in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, 40-055 Katowice, Poland.
Katarzyna StęplewskaDepartment of Pathology, Institute of Medical Sciences, University of Opole, 45-052 Opole, Poland.ORCID 0000-0002-0971-2317
Medical University of Silesia · PLUniversity of Naples Federico II · ITUniversity of Opole · PL

Funding

Medical University of Silesia PCN-1-181/N/1/I
6 · The paper itself

Abstract

Glutathione peroxidase 2 (Gpx-2) is a selenoenzyme with antioxidant capabilities that may play a role in cancer development. Hence, we investigated the immunohistochemical expression of Gpx-2 protein in colon adenocarcinoma samples derived from patients with colon adenocarcinoma who did not receive any form of treatment prior to the surgical procedure. The associations between the immunohistochemical expression of Gpx-2 and clinical parameters were analysed using the Chi

Indexed as

AdenocarcinomaColonic NeoplasmsClinical RelevanceGlutathione PeroxidaseHumansGlutathione Peroxidase5-year survivalcolon adenocarcinomaglutathione peroxidaseimmunogold labellingimmunohistochemistryoxidative stressprognostic marker

Identifiers

PMID37834097
PMCPMC10572251
OpenAlexW4387138009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.