Evidence map›Paper›PMID 37834041›Full record

ArticleInternational journal of molecular sciences2023

Human Papillomavirus 16 DNA Methylation Patterns and Investigation of Integration Status in Head and Neck Cancer Cases.

Ioannis Zygouras, Danai Leventakou, Abraham Pouliakis, Styliana Panagiotou, Dimitris Tsakogiannis, Georgios Konstantopoulos, Eirini Logotheti, Menelaos Samaras, Zaharoula Kyriakopoulou, Apostolos Beloukas and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Head and neck squamous cell carcinoma: current and emerging therapeutic strategies.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Review
  3. Article
  4. Disruption Events in the HPV18International journal of molecular sciences · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. HPV16Viruses · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Ioannis ZygourasDepartment of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Danai Leventakou2nd Department of Pathology, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, 12464 Athens, Greece.
Abraham Pouliakis2nd Department of Pathology, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, 12464 Athens, Greece.ORCID 0000-0002-0074-3619
Styliana PanagiotouDepartment of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Dimitris TsakogiannisResearch Center, Hellenic Anticancer Institute, 10680 Athens, Greece.ORCID 0000-0001-6835-8410
Georgios KonstantopoulosDepartment of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Eirini LogothetiDepartment of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Menelaos Samaras2nd Department of Pathology, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, 12464 Athens, Greece.
Zaharoula KyriakopoulouDepartment of Environment, School of Technology, University of Thessaly, Gaiopolis Campus, 41500 Larissa, Greece.ORCID 0000-0002-2424-6772
Apostolos BeloukasDepartment of Biomedical Sciences, University of West Attica, 12243 Athens, Greece.ORCID 0000-0001-5639-0528
Ioannis S Pateras2nd Department of Pathology, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, 12464 Athens, Greece.
Alexandros Delides2nd Department of Otolaryngology, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, 12464 Athens, Greece.
Amanda Psyrri2nd Department of Internal Medicine-Propaedeutic, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, 12464 Athens, Greece.
Ioannis G Panayiotides2nd Department of Pathology, University General Hospital "Attikon", School of Medicine, National and Kapodistrian University of Athens, 12464 Athens, Greece.
Minas YiangouDepartment of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Christine KottaridiDepartment of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-0979-3871
National and Kapodistrian University of Athens · GRAristotle University of Thessaloniki · GRUniversity of Thessaly · GRUniversity of West Attica · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent high-risk human papillomavirus (HPV) infection is a pivotal factor in the progression of cervical cancer. In recent years, an increasing interest has emerged in comprehending the influence of HPV on head and neck squamous cell carcinoma (HNSCC). Notably, it is well established that HPV-associated HNSCC show cases with distinct molecular and clinical attributes compared to HPV-negative cases. The present study delves into the epigenetic landscape of HPV16, specifically its

Indexed as

Carcinoma, Squamous CellHead and Neck NeoplasmsOncogene Proteins, ViralPapillomavirus InfectionsDNADNA MethylationDNA, ViralFemaleHuman Papillomavirus VirusesHumansSquamous Cell Carcinoma of Head and NeckDNADNA, ViralOncogene Proteins, ViralHNSCCHPV16L1UTR methylationviral integration

Identifiers

PMID37834041
PMCPMC10572864
OpenAlexW4387101998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.