Evidence map›Paper›PMID 37833929›Full record

ArticleInternational journal of molecular sciences2023

Structure-Activity Relationships and Antiplasmodial Potencies of Novel 3,4-Disubstituted 1,2,5-Oxadiazoles.

Patrick Hochegger, Theresa Hermann, Johanna Dolensky, Werner Seebacher, Robert Saf, Eva-Maria Pferschy-Wenzig, Marcel Kaiser, Pascal Mäser, Robert Weis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bioactive Oxadiazoles 3.0.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Patrick HocheggerInstitute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstraße 1, A-8010 Graz, Austria.
Theresa HermannInstitute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstraße 1, A-8010 Graz, Austria.ORCID 0000-0002-5267-7852
Johanna DolenskyInstitute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstraße 1, A-8010 Graz, Austria.
Werner SeebacherInstitute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstraße 1, A-8010 Graz, Austria.ORCID 0000-0002-5673-0470
Robert SafInstitute for Chemistry and Technology of Materials (ICTM), Graz University of Technology, Stremayrgasse 9, A-8010 Graz, Austria.
Eva-Maria Pferschy-WenzigInstitute of Pharmaceutical Sciences, Pharmacognosy, University of Graz, Beethovenstraße 8, A-8010 Graz, Austria.ORCID 0000-0001-8327-0732
Marcel KaiserSwiss Tropical and Public Health Institute, Kreuzstraße 2, CH-4123 Allschwil, Switzerland.ORCID 0000-0003-1785-7302
Pascal MäserSwiss Tropical and Public Health Institute, Kreuzstraße 2, CH-4123 Allschwil, Switzerland.ORCID 0000-0003-3122-1941
Robert WeisInstitute of Pharmaceutical Sciences, Pharmaceutical Chemistry, University of Graz, Schubertstraße 1, A-8010 Graz, Austria.ORCID 0000-0002-7174-6673

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 4-substituted 3-amino-1,2,5-oxadiazole

Indexed as

AntimalarialsMalariaMalaria, FalciparumChloroquineHumansPlasmodium falciparumStructure-Activity RelationshipAntimalarialsChloroquine1,2,5-oxadiazolesantimalarialCYP3A4-inhibitionPlasmodium falciparumsolubility

Identifiers

PMID37833929
PMCPMC10572347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.