Evidence map›Paper›PMID 37833652›Full record

ReviewInternational journal of emergency medicine2023

Diagnosis and management of elevated intracranial pressure in the emergency department.

Sima Patel, Jose Maria-Rios, Amay Parikh, Okorie Nduka Okorie

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07786324 (Comparison of 3% Hypertonic Saline Versus 20% Mannitol in Reduction of Increased Intracranial Pressure in Patients With Traumatic Brain Injury Using Optic Nerve Sheath Diameter Measurements''), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07786324 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of 3% Hypertonic Saline Versus 20% Mannitol in Reduction of Increased Intracranial Pressure in Patients With Traumatic Brain Injury Using Optic Nerve Sheath Diameter Measurements''

TypeinterventionalSponsorAssiut UniversityRan2026 to 2029Enrolled100ConditionsTBI (Traumatic Brain Injury), ICP (Intracranial Pressure) Increase, Optic Nerve Sheath Diameter MeasurementArmsMannitol (20%), Hypertonic Saline ( 3% Sodium Chloride Saline)
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Sedation and analgesia strategies in the neuro intensive care unit.World journal of critical care medicine · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Ominous Causes of Headache.Current pain and headache reports · 2024
    Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sima PatelDepartment of Critical Care Medicine, AdventHealth Orlando, 601 E Rollins St, Orlando, FL, 32803, USA. a.patelsima@gmail.com.
Jose Maria-RiosDepartment of Critical Care Medicine, AdventHealth Orlando, 601 E Rollins St, Orlando, FL, 32803, USA.
Amay ParikhDivision of Neurocritical Care, Department of Critical Care Medicine, AdventHealth Orlando, 601 E Rollins St, Orlando, FL, 32803, USA.
Okorie Nduka OkorieDivision of Neurocritical Care, Department of Critical Care Medicine, AdventHealth Orlando, 601 E Rollins St, Orlando, FL, 32803, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElevated intracranial pressure is a devastating complication of catastrophic brain injury. Intracranial hypertension is commonly seen in neurologic injury secondary to traumatic brain injuries. Uncontrolled pressures can lead to permanent neurologic damage, but acute medical management is often overlooked when pursuing surgical management options that may not always be indicated. DISCUSSION: Traumatic brain injury is the leading cause of death in patients with severe neurologic injury. Diagnosing elevated intracranial pressures is imperative in initiating prompt treatment to reduce secondary central nervous system injury, morbidity, and mortality. Although the initial injury to the brain is typically irreversible, intracranial pressure control can assist in salvaging the remaining brain tissue from additional damage. We will discuss the initial medical and surgical management of traumatic brain injury to prevent further neurologic deterioration and reduce mortality.

conclusionRecent literature has reported several methods to detect elevated intracranial pressure easily and studies describing multiple treatment modalities. These investigations suggest that early detection and timely treatment of intracranial hypertension are beneficial in reducing mortality.

Indexed as

Elevated intracranial pressureEmergency departmentIntracranial hypertensionIntracranial pressureTraumatic brain injury

Identifiers

PMID37833652
PMCPMC10571389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.