ArticleWorld journal of urology2023
450-nm blue diode laser: a novel medical apparatus for upper tract urothelial lesions.
Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Efficacy analysis of 450 nm semiconductor blue laser enucleation of the prostate in treating benign prostatic hyperplasia with urinary retention.Lasers in medical science · 2025Article
- In silico design of blue laser soft tissue vaporization with optimized optical power efficiency and mitigated thermal side effects.Lasers in medical science · 2025Article
- Evaluation of Non-cross-linked Hyaluronic Acid on Oral Wound Healing After Diode Laser and Scalpel Incisions.Plastic and reconstructive surgery. Global open · 2025Article
- A Novel 450-nm Laser Technique Versus Electrosurgical Excision for Hysteroscopic Endometrial Polypectomy: Efficacy and Safety.Journal of lasers in medical sciences · 2025Article
- Measurement of tissue optical properties in the 400 to 700 nm range to assess light penetration depths for laser treatment of upper tract urothelial carcinomas.Journal of biomedical optics · 2024Article
- Consultation on UTUC Stockholm 2022.World journal of urology · 2023Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo explore the feasibility, safety and effectiveness of the 450-nm blue diode laser (BL), novel blue laser in the treatment of upper tract urothelial carcinomas (UTUCs) and other lesions in a porcine model. MATERIAL AND
methodsFor in vitro experiment, the ureter tissue was vaporised and coagulated with BL, green-light laser (GL) and Ho:YAG laser (Ho). The efficiency, width and depth of vaporisation, and depth of coagulation were recorded and compared. For in vivo experiments, four swines weighing 70 kg were used. In the acute group, different modes of operations were performed to evaluate the thermal damage, perforation and bleeding. In the chronic group, the overall appearance of the ureter and laser wound healing were observed by the naked eyes and H&E staining 3 weeks after surgery.
resultsIn in vitro study, the BL showed a higher efficiency of tissue vaporisation and less tissue coagulation for fresh ureter compared to GL and Ho. In the in vivo study, the power of BL set at 7 W was better, and the thickness of thermal damage varied with different surgery types in the range of 74-306 μm. After 3 weeks, the wound healed well static in vaporisation (SV), moving vaporisation (MV) and H&E staining indicated mucosal healing rather than scar healing.
conclusion5-10W blue diode laser achieved a higher efficiency of tissue vaporisation and less tissue coagulation in a porcine model, indicating its potential application in the endoscopic surgery of UTUC as an optional device with high performance and safety.
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