ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2024
Osteoporotic vertebral fractures localized in the lumbar area significantly impact sagittal alignment.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 11 citations in OpenAlex.
- The Elusive Concept of Stability in Osteoporotic Vertebral Fractures: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Association Between Lower Instrumented Vertebra Selection and Mechanical Complications After Surgical Correction for Kyphotic Deformity Following Osteoporotic Vertebral Fracture.Journal of clinical medicine · 2026Article
- Effect of Thoracolumbar Vertebral Body Fractures on the Prognosis of Dropped Head Syndrome.Spine surgery and related research · 2025Article
- Clinical Outcomes and Risk Factors Associated with Spinal Kyphotic Deformity Following Osteoporotic Vertebral Fracture.Journal of clinical medicine · 2025Article
- L5 osteotomy combined with adjuvant romosozumab therapy for L5 osteoporotic vertebral fracture-induced spinal deformity: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Addressing Biomechanical Errors in the Back Squat for Older Adults: A Clinical Perspective for Maintaining Neutral Spine and Knee Alignment.Journal of functional morphology and kinesiology · 2024Article
- Utility of Radiographic Parameter in Assessing Bone Density and Subsequent Fractures in Patients With Osteoporotic Vertebral Compression Fracture.Neurospine · 2024Article
- Spinal alignment and surgical correction in the aging spine and osteoporotic patient.North American Spine Society journal · 2024Review
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6 authors at 2 institutions in 1 country.
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Abstract
Lumbar fractures and/or multiple fractures at the lumbar or thoracolumbar regions are risk factors for sagittal malalignment in patients older than 70 years old. Although patients with OVF show a huge capacity to compensate after the fractures, lumbar and TL lumbar fractures require closer monitoring. PURPOSE: To assess the impact of osteoporotic vertebral fractures on the sagittal alignment of the elderly and identify risk factors for sagittal malalignment.
methodsWe performed a retrospective study on a cohort of 249 patients older than 70 years old and diagnosed with osteoporosis who suffered chronic vertebral fractures. Demographic and radiological data were collected. Full-spine lateral X-rays were obtained to analyze the sagittal plane. Patients were classified according to the number and location of the fractures. Pearson's correlation coefficient was used to assess the relationships between the type of fractures and sagittal alignment.
resultsA total of 673 chronic fractures were detected in 249 patients with a mean number of vertebral fractures per patient of 2.7 ± 1.9. Patients were divided into 9 subgroups according to the location and the number of fractures. Surprisingly, any of the aggregated parameters used to assess sagittal alignment exceeded the threshold defined for malalignment. In the second part of the analysis, 41 patients with sagittal malalignment were identified. In this subpopulation, an overrepresentation of patients with lumbar fractures (34% vs. 11%) and an under-representation of thoracic fractures (9% vs. 34%) were reported. We also observed that patients with 3 or more lumbar or thoracolumbar fractures had an increased risk of sagittal malalignment.
conclusionsLumbar fractures and/or multiple fractures at the lumbar or thoracolumbar regions are risk factors for sagittal malalignment in patients older than 70 years old. Although patients show a remarkable capacity to compensate, fractures at the lumbar and thoracolumbar regions need closer monitoring.
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