Evidence map›Paper›PMID 37833518›Full record

ArticleSleep & breathing = Schlaf & Atmung2024

Do nocturnal asthma attacks influence sleep parameters and inflammatory markers? A cross-sectional population-based study.

Maingredy Rodrigues Souza, Daniela Santoro Rosa, Tathiana A Alvarenga, Priscila K Morelhão, Sergio Tufik, Monica L Andersen

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Maingredy Rodrigues SouzaSleep Institute, São Paulo, Brazil.
Daniela Santoro RosaDepartamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo, São Paulo, Brazil.
Tathiana A AlvarengaSleep Institute, São Paulo, Brazil.
Priscila K MorelhãoSleep Institute, São Paulo, Brazil.
Sergio TufikSleep Institute, São Paulo, Brazil.
Monica L AndersenSleep Institute, São Paulo, Brazil. ml.andersen12@gmail.com.ORCID 0000-0002-1894-6748
Universidade Federal de São Paulo · BRSleep Management Institute · US

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2020/13467-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/13004-0
6 · The paper itself

Abstract

purposeTo evaluate the effects of nocturnal asthma on sleep parameters and inflammatory markers according to the severity of the condition in participants in the São Paulo Epidemiologic Sleep Study (EPISONO).

methodsData from the 2007 and 2018 editions of the EPISONO study were utilized. Subjects completed validated sleep and respiratory questionnaires, underwent nocturnal polysomnography and spirometry tests, and provided blood samples for the assessment of inflammatory parameters.

resultsOf 72 participants (67% women), 53% (n = 38) had intermittent nocturnal asthma symptoms and 47% (n = 34) had persistent asthma (mild, moderate, and severe). Individuals with persistent nocturnal symptoms had a higher body mass index (BMI), were more likely to have respiratory symptoms, and had worse lung function, a higher apnea-hypopnea index (AHI), and higher desaturation index than individuals with intermittent nocturnal symptoms. Positive associations were identified between nocturnal asthma and obstructive sleep apnea (OSA). A higher frequency of OSA was observed in participants with persistent asthma and participants with OSA were more likely to have persistent than intermittent asthma. However, there were no significant differences between the immunological parameters of those with intermittent or persistent asthma.

conclusionsThis study highlights the relevance of nocturnal symptoms as a valuable indicator of asthma severity. The findings also add to the existing body of evidence linking nocturnal asthma and OSA.

Indexed as

AsthmaPolysomnographySleep Apnea, ObstructiveAdultBiomarkersBrazilCross-Sectional StudiesFemaleHumansInflammationMaleMiddle AgedSeverity of Illness IndexBiomarkersAsthmaInflammationObstructive sleep apneaSleep

Identifiers

PMID37833518
OpenAlexW4387637126

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.