Evidence map›Paper›PMID 37833441›Full record

SynthesisDigestive diseases and sciences2023

What Is the Optimal Bowel Preparation for Capsule Colonoscopy and Pan-intestinal Capsule Endoscopy? A Systematic Review and Meta-Analysis.

Bruno Rosa, Helena Donato, Tiago Cúrdia Gonçalves, Bernardo Sousa-Pinto, José Cotter

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Digestive diseases and sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07206329 (A Prospective Study Comparing Ultra-Low Volume Bowel Preparations for Capsule Colonoscopy and Pan-Intestinal Capsule Endoscopy), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07206329 nacompletednot on this mapstarted 2024, after this paper: background citation

A Prospective Study Comparing Ultra-Low Volume Bowel Preparations for Capsule Colonoscopy and Pan-Intestinal Capsule Endoscopy: Efficacy of 1L Polyethylene Glycol Plus Ascorbic Acid vs. Sodium Picosulfate With Magnesium Citrate

TypeinterventionalSponsorUnidade Local de Saúde do Alto Ave, EPERan2024 to 2025Enrolled220ConditionsBowel Preparation SolutionArmsPolyethylene Glycol plus Ascorbic Acid (PEG-Asc), Sodium Picosulfate with Magnesium Citrate (SPMC)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Bruno RosaDepartment of Gastroenterology, Hospital da Senhora da Oliveira, Guimarães, Guimarães, Portugal. bruno.joel.rosa@gmail.com.ORCID 0000-0003-2885-0720
Helena DonatoDocumentation and Scientific Information Service, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0002-1905-1268
Tiago Cúrdia GonçalvesDepartment of Gastroenterology, Hospital da Senhora da Oliveira, Guimarães, Guimarães, Portugal.ORCID 0000-0001-5540-6452
Bernardo Sousa-PintoDepartment of Community Medicine, Information and Health Decision Sciences (MEDCIDS), Faculty of Medicine, University of Porto, Porto, Portugal.ORCID 0000-0002-1277-3401
José CotterDepartment of Gastroenterology, Hospital da Senhora da Oliveira, Guimarães, Guimarães, Portugal.ORCID 0000-0002-2921-0648
Hospital da Senhora da Oliveira Guimarães · PTHospitais da Universidade de Coimbra · PTUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe rate of adequate cleansing (ACR) and complete examinations (CR) are key quality indicators in capsule colonoscopy (CC) and pan-intestinal capsule endoscopy (PCE).

aimsTo evaluate the efficacy of bowel preparation protocols regarding ACR and CR.

methodsWe conducted a systematic review and meta-analysis, search terms regarding colon capsule preparation, publication date from 2006/01, and date of search 2021/12, in six bibliographic databases. Multiple steps of the cleansing protocol were assessed: diet, adjunctive laxatives, purgative solution, use of prokinetic agents, and "booster". The meta-analytical frequency of ACR and CR was estimated, and subgroup analyses performed. Strategies associated with higher ACR and CR were explored using meta-analytical univariable and multivariable regression models.

resultsTwenty-six observational studies and five RCTs included (n = 4072 patients). The pooled rate of ACR was 72.5% (95% C.I. 67.8-77.5%; I

conclusionsMain quality outcomes (ACR, CR) remain suboptimal for CC and PCE. Despite considerable heterogeneity, our results support low-fibre diet, use of adjunctive sennosides, split dose < 4L PEG, and routine prokinetics, while NaP remains the most consistent option as booster.

Indexed as

Capsule EndoscopyCatharticsColonoscopyHumansLaxativesPolyethylene GlycolsCatharticsLaxativesPolyethylene GlycolsBowel preparationCapsule colonoscopyPan-intestinal capsule endoscopy

Identifiers

PMID37833441
PMCPMC10635919
OpenAlexW4387614051

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.