Evidence map›Paper›PMID 37833355›Full record

ArticleScientific reports2023

Characterization and regulation of salt upregulated cyclophilin from a halotolerant strain of Penicillium oxalicum.

Mangaljeet Singh, Harpreet Singh, Kirandeep Kaur, Shubhankar Shubhankar, Supreet Singh, Amarjeet Kaur, Prabhjeet Singh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mangaljeet SinghDepartment of Biotechnology, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Harpreet SinghDepartment of Bioinformatics, Hans Raj Mahila Maha Vidyalaya, Jalandhar, Punjab, 144008, India.
Kirandeep KaurDepartment of Biotechnology, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Shubhankar ShubhankarDepartment of Biotechnology, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Supreet SinghDepartment of Biotechnology, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Amarjeet KaurDepartment of Microbiology, Guru Nanak Dev University, Amritsar, Punjab, 143005, India.
Prabhjeet SinghDepartment of Biotechnology, Guru Nanak Dev University, Amritsar, Punjab, 143005, India. singhprabhjeet62@gmail.com.
Guru Nanak Dev University · INHans Raj Mahila Maha Vidyalaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penicillium species are an industrially important group of fungi. Cyclophilins are ubiquitous proteins and several members of this family exhibit peptidyl-prolyl cis-trans isomerase (PPIase) activity. We had earlier demonstrated that the salt-induced PPIase activity in a halotolerant strain of P. oxalicum was associated with enhanced expression of a cyclophilin gene, PoxCYP18. Cloning and characterization of PoxCYP18 revealed that its cDNA consists of 522 bp encoding a protein of 173 amino acid residues, with predicted molecular mass and pI values of 18.91 kDa and 8.87, respectively. The recombinant PoxCYP18 can catalyze cis-trans isomerization of peptidyl-prolyl bond with a catalytic efficiency of 1.46 × 10

Indexed as

CyclophilinsPenicilliumCyclosporineEscherichia coliPeptidylprolyl IsomeraseCyclophilinsCyclosporinePeptidylprolyl Isomerase

Identifiers

PMID37833355
PMCPMC10575979
OpenAlexW4387608764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.