Evidence map›Paper›PMID 37833299›Full record

ArticleScientific reports2023

Ganoderma lucidum methanolic extract as a potent phytoconstituent: characterization, in-vitro antimicrobial and cytotoxic activity.

Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi, Ahmad Gholami, Navid Omidifar, Wei-Hung Chiang, Vijayakameswara Rao Neralla, Khadije Yousefi, Mansoureh Shokripour

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. From Mushrooms to Molecules: Exploring Depsidones inMolecules (Basel, Switzerland) · 2025
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  6. Exploring the health benefits ofFrontiers in cellular and infection microbiology · 2025
    Review
  7. Review
  8. Heliyon · 2024
    Review
  9. DoMolecules (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Seyyed Mojtaba MousaviDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
Seyyed Alireza HashemiHealth Policy Research Center, Health Institute, Shiraz University of Medica Sciences, Shiraz, Iran.
Ahmad GholamiBiotechnology Research Center, Shiraz University of Medical Sciences, P.O. Box: 71348-14336, Shiraz, Iran. Gholami@sums.ac.ir.
Navid OmidifarBiotechnology Research Center, Shiraz University of Medical Sciences, P.O. Box: 71348-14336, Shiraz, Iran. omidifar@gmail.com.
Wei-Hung ChiangDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan. whchiang@mail.ntust.edu.tw.
Vijayakameswara Rao NerallaDepartment of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
Khadije YousefiBiotechnology Research Center, Shiraz University of Medical Sciences, P.O. Box: 71348-14336, Shiraz, Iran.
Mansoureh ShokripourDepartment of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
National Taiwan University of Science and Technology · TWShiraz University of Medical Sciences · IRBiotechnology Research Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ganoderma lucidum methanolic extract (GLME) has attracted tremendous attention due to its exceptional antimicrobial and anticancer properties that can be delicately tuned by controlling the initial extraction's content and concentration. Herein, we detailed the characterization, antimicrobial, and cytotoxic performance of GLME as a potential multi-functional therapeutic agent. Accordingly, FTIR, XRD, FESEM, EDX, and HPLC analyses were employed to assess the samples, followed by disc diffusion and microdilution broth methods to test its antibacterial effects against four Gram-positive and Gram-negative bacterial strains, viz., Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. MTT assay was applied to determine the cytotoxic activity of GLME against PDL and Hek-293 normal cell lines and MCF-7 and K-562 cancer cell lines. The IC50 values of 598 µg mL

Indexed as

Antineoplastic AgentsReishiAnti-Bacterial AgentsBacteriaHEK293 CellsHumansMethanolMicrobial Sensitivity TestsPlant ExtractsAnti-Bacterial AgentsAntineoplastic AgentsMethanolPlant Extracts

Identifiers

PMID37833299
PMCPMC10576041
OpenAlexW4387616681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.