ArticleNature communications2023
Developmental atlas of phase-amplitude coupling between physiologic high-frequency oscillations and slow waves.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Internal and external validation of comprehensive high-frequency activity biomarkers for epilepsy surgery.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Article
- Inroads into epilepsy through high-frequency oscillations: Achievements and benchmark areas for improvement.Epilepsia · 2026Review
- ESM-AnatTractNet: Advanced deep learning model of true positive eloquent white matter tractography to improve preoperative evaluation of pediatric epilepsy surgery.Medical image analysis · 2026Article
- Whole-Brain Dynamic Causal Tractography Atlas of Auditory and Visual Speech Networks Derived From Intracranial Neurophysiologic Data.Neurology · 2026Observational
- Internal and External Validation of Comprehensive High-Frequency Activity Biomarkers for Epilepsy Surgery.medRxiv : the preprint server for health sciences · 2025Article
- Self-supervised data-driven approach defines pathological high-frequency oscillations in epilepsy.Epilepsia · 2025Article
- Visual Features in Stereo-Electroencephalography to Predict Surgical Outcome: A Multicenter Study.Annals of neurology · 2025Article
- Localization of the Epileptogenic Zone Using Neural Spatial Volatility in Epilepsy Surgery.Neurology · 2025Observational
- AI-based localization of the epileptogenic zone using intracranial EEG.Epilepsia open · 2025Review
- Article
- Dynamic Causal Tractography Analysis of Auditory Descriptive Naming: An Intracranial Study of 106 Patients.NeuroImage · 2025Article
- Visualization of functional and effective connectivity underlying auditory descriptive naming.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025Article
- Very High-Frequency Oscillations in Mesial Temporal Lobe Epilepsy: Identifying the Epileptogenic Zone.Annals of clinical and translational neurology · 2025Article
- Mechanistic insights into the interaction between epilepsy and sleep.Nature reviews. Neurology · 2025Review
- Normative high-frequency oscillation phase-amplitude coupling and effective connectivity under sevoflurane.Brain communications · 2025Article
- Editorial: Advances in epilepsy research: exploring biomarkers, brain stimulation, and neurosurgical interventions.Frontiers in human neuroscience · 2025Article
- Noninvasive classification of physiological and pathological high frequency oscillations in children.Brain communications · 2025Article
- Normative atlases of high-frequency oscillation and spike rates under Sevoflurane anesthesia.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024Article
- Article
- How to design optimal brain stimulation to modulate phase-amplitude coupling?Journal of neural engineering · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
We investigated the developmental changes in high-frequency oscillation (HFO) and Modulation Index (MI) - the coupling measure between HFO and slow-wave phase. We generated normative brain atlases, using subdural EEG signals from 8251 nonepileptic electrode sites in 114 patients (ages 1.0-41.5 years) who achieved seizure control following resective epilepsy surgery. We observed a higher MI in the occipital lobe across all ages, and occipital MI increased notably during early childhood. The cortical areas exhibiting MI co-growth were connected via the vertical occipital fasciculi and posterior callosal fibers. While occipital HFO rate showed no significant age-association, the temporal, frontal, and parietal lobes exhibited an age-inversed HFO rate. Assessment of 1006 seizure onset sites revealed that z-score normalized MI and HFO rate were higher at seizure onset versus nonepileptic electrode sites. We have publicly shared our intracranial EEG data to enable investigators to validate MI and HFO-centric presurgical evaluations to identify the epileptogenic zone.
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