Evidence map›Paper›PMID 37833062›Full record

ArticleeNeuro2023

Plasticity in Preganglionic and Postganglionic Neurons of the Sympathetic Nervous System during Embryonic Development.

April Ratliff, Dobromila Pekala, Peter Wenner

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

April RatliffDepartment of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322.
Dobromila PekalaDepartment of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322.
Peter WennerDepartment of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322 pwenner@emory.edu.ORCID 0000-0002-7072-2194
Emory University · US

Funding

The role of intrinsic cellular excitability in homeostatic plasticity of developing circuitsR01NS065992 · NINDS · EMORY UNIVERSITY · PI WENNER, PETER A · 2010 to 2024
$4.5M
Homeostatic plasticity in the homeostatic sympathetic nervous systemR21NS106325 · NINDS · EMORY UNIVERSITY · PI WENNER, PETER A · 2018 to 2019
$429k
Homeostatic Plasticity and Maturation of Excitability During Embryonic Development of the Sympathetic Nervous SystemF31NS118867 · NINDS · EMORY UNIVERSITY · PI RATLIFF, APRIL · 2020 to 2021
$92k
NINDS NIH HHS F31 NS118867NINDS NIH HHS R01 NS065992NINDS NIH HHS R21 NS106325
6 · The paper itself

Abstract

Sympathetic preganglionic neurons (SPNs) are the final output neurons from the central arm of the autonomic nervous system. Therefore, SPNs represent a crucial component of the sympathetic nervous system for integrating several inputs before driving the postganglionic neurons (PGNs) in the periphery to control end organ function. The mechanisms which establish and regulate baseline sympathetic tone and overall excitability of SPNs and PGNs are poorly understood. The SPNs are also known as the autonomic motoneurons (MNs) as they arise from the same progenitor line as somatic MNs that innervate skeletal muscles. Previously our group has identified a rich repertoire of homeostatic plasticity (HP) mechanisms in somatic MNs of the embryonic chick following

Indexed as

InterneuronsSpinal CordEmbryonic DevelopmentMotor NeuronsSympathetic Nervous Systemautonomic nervous systemchick embryohomeostatic plasticitysympathetic nervous systemsynaptic scaling

Identifiers

PMID37833062
PMCPMC10630925
OpenAlexW4387611529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.