ArticleScience advances2023
Glial-derived mitochondrial signals affect neuronal proteostasis and aging.
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Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
–field-weighted citation impact
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Who cites it
20 citing papers in PubMed.
- Neuronal expression of bromodomain proteins alters neuronal health and peripheral protein homeostasis to promote longevity.Genes & development · 2026Article
- The mitochondrial unfolded protein response in human microglia disrupts neuronal-glial communication and promotes senescence.Nature neuroscience · 2026Article
- Article
- Neuronal tetraspanin TSP-6 suppresses intestinal innate immunity by modulating dense-core vesicle release in Caenorhabditis elegans.Cell communication and signaling : CCS · 2026Article
- Adaptive inter-tissue proteostasis networks in aging and neurodegeneration.Bioscience reports · 2026Review
- Glial overexpression of carbonic anhydrasemicroPublication biology · 2026Article
- TDP-43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models.The FEBS journal · 2026Review
- Unraveling sex differences in age-related hippocampal decline: differential mitochondrial dysfunction, Lonp1-dependent mitochondrial proteostasis and mtROS production in aged C57BL/6 mice.Cell death & disease · 2025Article
- The microRNA miR-71 suppresses maladaptive UPRNature communications · 2025Article
- Distinct responses to non-autonomous UPRCommunications biology · 2025Article
- The loss of a ClC anion channel increases life span, health span, and stress resistance by alkalinizing a pair of glial cells inScience advances · 2025Article
- Interplay Between Aging and Glial Cell Dysfunction: Implications for CNS Health.Life (Basel, Switzerland) · 2025Review
- LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes.Nature metabolism · 2025Article
- Brain Metabolism in Health and Neurodegeneration: The Interplay Among Neurons and Astrocytes.Cells · 2024Review
- GlialProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Inhibition of a cyclic nucleotide-gated channel on neuronal cilia activates unfolded protein response in intestinal cells to promote longevity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Mechanical stress through growth on stiffer substrates impacts animal health and longevity inbioRxiv : the preprint server for biology · 2024Article
- Article
- Mitophagy in Alzheimer's Disease: A Bibliometric Analysis from 2007 to 2022.Journal of Alzheimer's disease reports · 2024Article
- Simple models to understand complex disease: 10 years of progress fromFrontiers in neuroscience · 2023Review
Corrections and comments
- Update of
Authors and funding
17 authors.
Raz Bar-ZivDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-2615-1942
Naibedya DuttaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Adam HrubyLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0002-1970-1312
Edward SukartoDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-2292-4266
Maxim AverbukhLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0002-8516-5714
Athena AlcalaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Hope R HendersonDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-1373-296X
Jenni DurieuxDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-0016-7332
Sarah U TronnesDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0001-5357-046X
Qazi AhmadDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-0702-1050
Theodore BolasDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.
Joel PerezDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-2282-0566
Julian G DishartDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0003-0014-6141
Matthew VegaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Gilberto GarciaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0001-9959-650X
Ryo Higuchi-SanabriaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.ORCID 0000-0001-8936-5812
Andrew DillinDepartment of Molecular and Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-7427-2629
Funding
Wormbase SupplementP41HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI STERNBERG, PAUL WARREN · 2000 to 2012
$32.0MWormBase: a core data resource for C. elegans and other nematodesU41HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI KERSEY, PAUL, SCHEDL, TIM · 2013 to 2017
$20.5MWormBase: a core data resource for C. elegans and other nematodesU24HG002223 · NHGRI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI TIM SCHEDL, PAUL Warren STERNBERG · 2018 to 2026
$18.9MEnhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5MNeuroscience Training Program at UC BerkeleyT32NS095939 · NINDS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BATEUP, HELEN S. · 2016 to 2025
$6.3MUSC Geroscience Training in the Biology of AgingT32AG052374 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sean P CURRAN · 2016 to 2026
$5.3MNeuroendocrine Coordination of Mitochondrial Stress Signaling and ProteostasisR01ES021667 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 2012 to 2023
$4.6MMore than just a load control: cytoskeletal form and function during agingR00AG065200 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIGUCHI-SANABRIA, RYO · 2021 to 2023
$747kNHGRI NIH HHS P41 HG002223NHGRI NIH HHS U24 HG002223NHGRI NIH HHS U41 HG002223NIA NIH HHS R00 AG065200NIA NIH HHS T32 AG052374NIEHS NIH HHS R01 ES021667NIH HHS P40 OD010440
Abstract
The nervous system plays a critical role in maintaining whole-organism homeostasis; neurons experiencing mitochondrial stress can coordinate the induction of protective cellular pathways, such as the mitochondrial unfolded protein response (UPR
Indexed as
Caenorhabditis elegans ProteinsProteostasisAgingAnimalsCaenorhabditis elegansNeurogliaNeuronsCaenorhabditis elegans Proteins
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.