Evidence map›Paper›PMID 37831760›Full record

ArticleScience immunology2023

IL-31-dependent neurogenic inflammation restrains cutaneous type 2 immune response in allergic dermatitis.

Marlys S Fassett, Joao M Braz, Carlos A Castellanos, Juan J Salvatierra, Mahsa Sadeghi, Xiaobing Yu, Andrew W Schroeder, Jaela Caston, Priscila Munoz-Sandoval, Suparna Roy and 6 more

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Human germline biallelic loss-of-functionJournal of human immunity · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Therapeutic advances in pruritus as a model of personalized medicine.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Marlys S FassettDepartment of Dermatology, University of California, San Francisco, CA, USA.ORCID 0000-0002-5750-1928
Joao M BrazDepartment of Anatomy, University of California, San Francisco, CA, USA.ORCID 0000-0001-8955-0735
Carlos A CastellanosDepartment of Microbiology and Immunology, University of California, San Francisco, CA, USA.ORCID 0000-0003-3615-2009
Juan J SalvatierraDepartment of Anatomy, University of California, San Francisco, CA, USA.
Mahsa SadeghiDepartment of Anatomy, University of California, San Francisco, CA, USA.ORCID 0000-0002-9769-4082
Xiaobing YuDepartment of Anatomy, University of California, San Francisco, CA, USA.ORCID 0000-0001-6702-6203
Andrew W SchroederSandler Asthma Basic Research Center (SABRe), San Francisco, CA, USA.
Jaela CastonDepartment of Dermatology, University of California, San Francisco, CA, USA.
Priscila Munoz-SandovalDepartment of Dermatology, University of California, San Francisco, CA, USA.ORCID 0009-0005-7225-2615
Suparna RoyDepartment of Dermatology, University of California, San Francisco, CA, USA.ORCID 0000-0001-9007-8706
Steven LazarevskyDepartment of Dermatology, University of California, San Francisco, CA, USA.ORCID 0009-0009-4278-517X
Darryl J MarDepartment of Microbiology and Immunology, University of California, San Francisco, CA, USA.ORCID 0000-0002-8471-9930
Connie J ZhouDepartment of Microbiology and Immunology, University of California, San Francisco, CA, USA.ORCID 0000-0002-0099-0628
Jeoung-Sook ShinDepartment of Microbiology and Immunology, University of California, San Francisco, CA, USA.ORCID 0000-0002-0711-8234
Allan I BasbaumDepartment of Anatomy, University of California, San Francisco, CA, USA.ORCID 0000-0002-1710-6333
K Mark AnselDepartment of Microbiology and Immunology, University of California, San Francisco, CA, USA.ORCID 0000-0003-4840-9879
University of California, San Francisco · USSanden (Japan) · JPHoward Hughes Medical Institute · US

Funding

Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GERMAN, MICHAEL S · 2003 to 2019
$21.8M
From the spinal cord to the brain: Neurology of the pain and itch neuronsR35NS097306 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BASBAUM, ALLAN I. · 2017 to 2024
$7.2M
Comprehensive Anesthesia Research TrainingT32GM008440 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Judith Hellman · 1996 to 2026
$5.5M
Role of miRNAs in Th2-Driven inflammation in AsthmaR01HL109102 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Karl Mark Ansel · 2011 to 2026
$5.5M
Restorative practice in repairing harm and promoting safe and inclusive practices in the laboratory.T32GM136547 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Adrian Erlebacher, Anita Sil · 2020 to 2026
$4.5M
Interleukin-31 at the neuroimmune interface of pruritus and dermatitisK08AR074556 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FASSETT, MARLYS S · 2019 to 2023
$887k
Illuminating IL-31-producing cells in allergic skin diseaseR03AR082948 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FASSETT, MARLYS S · 2023 to 2023
$162k
NHLBI NIH HHS R01 HL109102NIAMS NIH HHS K08 AR074556NIAMS NIH HHS R03 AR082948NIDDK NIH HHS P30 DK063720NIGMS NIH HHS T32 GM008440NIGMS NIH HHS T32 GM136547NINDS NIH HHS R35 NS097306
6 · The paper itself

Abstract

Despite robust literature associating IL-31 with pruritic inflammatory skin diseases, its influence on cutaneous inflammation and the interplay between inflammatory and neurosensory pathways remain unmapped. Here, we examined the consequences of disrupting

Indexed as

Dermatitis, AtopicNeurogenic InflammationAnimalsCytokinesImmunityInterleukinsMicePyroglyphidaeSkinCytokinesinterleukin-31, mouseInterleukins

Identifiers

PMID37831760
PMCPMC10890830
OpenAlexW4387628508

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.