Evidence map›Paper›PMID 37831756›Full record

ArticleACS infectious diseases2023

Nitric Oxide-Induced Morphological Changes to Bacteria.

Huan K Nguyen, Samantha L Picciotti, Magdalena M Duke, Christopher A Broberg, Mark H Schoenfisch

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Nitric Oxide-ReleasingPharmaceutics · 2025
    Article
  4. Flow cytometry study ofFrontiers in microbiology · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Huan K NguyenDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Samantha L PicciottiDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Magdalena M DukeDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Christopher A BrobergDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Mark H SchoenfischDepartment of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID 0000-0002-2212-0658
University of North Carolina at Chapel Hill · US

Funding

Nitric oxide-releasing hyaluronic acid therapeutics for treating periodontal diseaseR01DE032060 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mark H Schoenfisch, Shannon Margaret Wallet · 2023 to 2026
$2.0M
Nitric oxide-releasing glycosaminoglycans for treating complex woundsR01DK132778 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mark H Schoenfisch, Shannon Margaret Wallet · 2023 to 2026
$1.5M
NIDCR NIH HHS R01 DE032060NIDDK NIH HHS R01 DK132778
6 · The paper itself

Abstract

Antimicrobial resistance poses a serious threat to global health, necessitating research for alternative approaches to treating infections. Nitric oxide (NO) is an endogenously produced molecule involved in multiple physiological processes, including the response to pathogens. Herein, we employed microscopy- and fluorescence-based techniques to investigate the effects of NO delivered from exogenous NO donors on the bacterial cell envelopes of pathogens, including resistant strains. Our goal was to assess the role of NO donor architecture (small molecules, oligosaccharides, dendrimers) on bacterial wall degradation to representative Gram-negative bacteria (

Indexed as

Anti-Bacterial AgentsNitric OxideGram-Negative BacteriaGram-Positive BacteriaStaphylococcus aureusAnti-Bacterial AgentsNitric Oxideantimicrobial resistanceESKAPE pathogensmorphological Changesnitric oxideNO-releasing dendrimerpositively charged quaternary ammonium

Identifiers

PMID37831756
PMCPMC11041245
OpenAlexW4387609305

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.