Evidence map›Paper›PMID 37831120›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2024

A Population-Based Family Case-Control Study of Sun Exposure and Follicular Lymphoma Risk.

Michael K Odutola, Marina T van Leeuwen, Fiona Bruinsma, Jennifer Turner, Mark Hertzberg, John F Seymour, H Miles Prince, Judith Trotman, Emma Verner, Fernando Roncolato and 8 more

Abstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Michael K OdutolaCentre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-3612-3702
Marina T van LeeuwenCentre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-1570-2852
Fiona BruinsmaCancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.ORCID 0000-0002-9356-2015
Jennifer TurnerAnatomical Pathology, Douglass Hanly Moir Pathology, Macquarie Park, Sydney, Australia.ORCID 0000-0001-5550-3375
Mark HertzbergDepartment of Haematology, Prince of Wales Hospital and University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0001-8495-4669
John F SeymourSir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0003-2188-6835
H Miles PrinceSir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0002-0058-2448
Judith TrotmanConcord Repatriation General Hospital, Concord, New South Wales, Australia.ORCID 0000-0001-8009-4593
Emma VernerConcord Repatriation General Hospital, Concord, New South Wales, Australia.ORCID 0009-0004-4945-2574
Fernando RoncolatoSt. George Hospital, Kogarah, New South Wales, Australia.ORCID 0009-0007-9955-5928
Stephen OpatClinical Haematology, Monash Health, Clayton, Victoria, Australia.ORCID 0000-0002-0308-6458
Robert LindemanNew South Wales Health Pathology, Sydney, New South Wales, Australia.ORCID 0000-0003-2910-3698
Campbell TileyGosford Hospital, Gosford, New South Wales, Australia.ORCID 0000-0002-4314-0877
Samuel T MillikenSt. Vincent's Hospital, Sydney, New South Wales, Australia.ORCID 0000-0003-3368-5176
Craig R UnderhillBorder Medical Oncology Research Unit, Albury, New South Wales, Australia.ORCID 0000-0001-9335-2678
Geza BenkeSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.ORCID 0000-0001-9019-9364
Graham G GilesCancer Epidemiology Division, Cancer Council Victoria, Melbourne, Victoria, Australia.ORCID 0000-0003-4946-9099
Claire M VajdicCentre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales, Australia.ORCID 0000-0002-3612-8298

Funding

National Health and Medical Research Council (NHMRC) 1012141National Health and Medical Research Council (NHMRC) ID1006707
6 · The paper itself

Abstract

backgroundEpidemiologic evidence suggests an inverse association between sun exposure and follicular lymphoma risk.

methodsWe conducted an Australian population-based family case-control study based on 666 cases and 459 controls (288 related, 171 unrelated). Participants completed a lifetime residence and work calendar and recalled outdoor hours on weekdays, weekends, and holidays in the warmer and cooler months at ages 10, 20, 30, and 40 years, and clothing types worn in the warmer months. We used a group-based trajectory modeling approach to identify outdoor hour trajectories over time and examined associations with follicular lymphoma risk using logistic regression.

resultsWe observed an inverse association between follicular lymphoma risk and several measures of high lifetime sun exposure, particularly intermittent exposure (weekends, holidays). Associations included reduced risk with increasing time outdoors on holidays in the warmer months [highest category OR = 0.56; 95% confidence interval (CI), 0.42-0.76; Ptrend < 0.01], high outdoor hours on weekends in the warmer months (highest category OR = 0.71; 95% CI, 0.52-0.96), and increasing time outdoors in the warmer and cooler months combined (highest category OR = 0.66; 95% CI, 0.50-0.91; Ptrend 0.01). Risk was reduced for high outdoor hour maintainers in the warmer months across the decade years (OR = 0.71; 95% CI, 0.53-0.96).

conclusionsHigh total and intermittent sun exposure, particularly in the warmer months, may be protective against the development of follicular lymphoma. IMPACT: Although sun exposure is not recommended as a cancer control policy, confirming this association may provide insights regarding the future control of this intractable malignancy.

Indexed as

Lymphoma, FollicularSkin NeoplasmsAustraliaCase-Control StudiesHumansRisk FactorsSunlight

Identifiers

PMID37831120
PMCPMC10774741

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.