Evidence map›Paper›PMID 37831081›Full record

ArticleSocial psychiatry and psychiatric epidemiology2024

Short-term disengagement from early intervention service for first-episode psychosis: findings from the "Parma Early Psychosis" program.

Lorenzo Pelizza, Emanuela Leuci, Emanuela Quattrone, Silvia Azzali, Simona Pupo, Giuseppina Paulillo, Pietro Pellegrini, Marco Menchetti

Abstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
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  5. What autism features in first episode psychosis? Results from a 2-year follow-up study.European archives of psychiatry and clinical neuroscience · 2025
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lorenzo PelizzaDepartment of Biomedical and Neuromotor Sciences, "Alma Mater Studiorum", Università di Bologna, Viale Pepoli, 5, 40126, Bologna, BO, Italy. lorenzo.pelizza@unibo.it.
Emanuela LeuciDepartment of Mental Health and Pathological Addiction, Azienda USL di Parma, Parma, PR, Italy.
Emanuela QuattroneDepartment of Mental Health and Pathological Addiction, Azienda USL di Parma, Parma, PR, Italy.
Silvia AzzaliDepartment of Mental Health and Pathological Addiction, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, RE, Italy.
Simona PupoPain Therapy Service, Department of Medicine and Surgery, Azienda Ospedaliero-Universitaria di Parma, Parma, PR, Italy.
Giuseppina PaulilloPain Therapy Service, Department of Medicine and Surgery, Azienda Ospedaliero-Universitaria di Parma, Parma, PR, Italy.
Pietro PellegriniDepartment of Mental Health and Pathological Addiction, Azienda USL di Parma, Parma, PR, Italy.
Marco MenchettiDepartment of Biomedical and Neuromotor Sciences, "Alma Mater Studiorum", Università di Bologna, Viale Pepoli, 5, 40126, Bologna, BO, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeService disengagement is a major concern for "Early Intervention in Psychosis" (EIP). Indeed, identifying predictors of engagement is crucial to maximize mental healthcare interventions in first-episode psychosis (FEP). No Italian study on this topic has been reported to date. Thus, the aims of this investigation were: (1) to examine short-term disengagement rate in an Italian population of FEP patients treated within an EIP service across a 1-year follow-up period, and (b) to assess the most relevant predictors of disengagement in the first year of treatment.

methodsAll participants were young FEP help-seeking patients, aged 12-35 years, enrolled within the "Parma Early Psychosis" (Pr-EP) protocol. At baseline, they completed the Positive And Negative Syndrome Scale (PANSS), the Health of the Nation Outcome Scale (HoNOS) and the Global Assessment of Functioning (GAF) scale. Univariate and multivariate Cox regression analyses were used.

results496 FEP individuals were enrolled in this research. Across the follow-up, a 16.5% prevalence of short-term disengagement was found. Particularly robust predictors of service disengagement were poor baseline treatment non-adherence, living with parents and the presence of brief psychotic disorder or schizophreniform disorder at entry.

conclusionAbout 16% of FEP patients disengaged the Pr-EP program within the first year of treatment. A solution to reduce disengagement and/or to favor re-engagement of these subjects might be to remain on EIP program caseloads allowing the option for low-intensity support and monitoring, also via remote technology.

Indexed as

Early Medical InterventionPsychotic DisordersAdolescentAdultChildFemaleFollow-Up StudiesHumansItalyMaleMental Health ServicesPatient Acceptance of Health CarePsychiatric Status Rating ScalesYoung AdultDisengagementDrop-outEarly intervention in psychosisFirst-episode psychosisFollow-upOutcome

Identifiers

PMID37831081
PMCPMC11178576

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.