Evidence map›Paper›PMID 37831079›Full record

ArticleSocial psychiatry and psychiatric epidemiology2024

Development and validation of the risk score for estimating suicide attempt in patients with major depressive disorder.

Zhi-Xin Huang, Qizhang Wang, Shasha Lei, Wenli Zhang, Ying Huang, Caiping Zhang, Xiangyang Zhang

Abstract readValidation Study
PubMed Publisher
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Zhi-Xin Huang *Department of Neurology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Qizhang Wang *Department of Neurology, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen, Guangdong, China.
Shasha LeiJinan University Faculty of Medical Science, Guangzhou, Guangdong, China.
Wenli ZhangDepartment of Neurology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Ying HuangDepartment of Neurology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, China.
Caiping ZhangGuangdong Medical University, Zhanjiang, Guangdong, China.
Xiangyang ZhangCAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Chaoying District, Beijing, 100101, China. zhangxy@psych.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early identification of high-risk patients with Major depressive disorder (MDD) having suicide attempts (SAs) is essential for timely targeted and tailored psychological interventions and medications. This study aimed to develop and validate a web-based dynamic nomogram as a personalized predictor of SA in MDD patients. A dynamic nomogram was developed using data collected from 1718 patients in China. The dynamic model was established based on a machine learning-based regression technique in the training cohort. We validated the nomogram internally using 1000 bootstrap replications. The nomogram performance was assessed using estimates of discrimination (via the concordance index) and calibration (calibration plots). The nomogram incorporated five predictors, including Hamilton anxiety rating scale (odds ratio [OR]: 1.255), marital status (OR: 0.618), clinical global impressions (OR: 2.242), anti-thyroid peroxidase antibodies (OR: 1.002), and systolic pressure levels (OR: 1.037). The model demonstrated good overall discrimination (Harrell's C-index = 0.823). Using decision curve analysis, this model also demonstrated good clinical applicability. An online web server was constructed ( https://odywong.shinyapps.io/PRSM/ ) to facilitate the use of the nomogram. Based on these results, our study developed a nomogram to predict SA in MDD patients. The application of this nomogram may help for patients and clinicians to make decisions.

Indexed as

Major Depressive DisorderNomogramsSuicide, AttemptedAdultChinaFemaleHumansMachine LearningMaleMiddle AgedPsychiatric Status Rating ScalesReproducibility of ResultsRisk AssessmentRisk FactorsAnxiety disordersDepressionMood disordersPsychotic disorderSuicide

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.