Evidence map›Paper›PMID 37830625›Full record

ArticleCells2023

Multiphoton In Vivo Microscopy of Embryonic Thrombopoiesis Reveals the Generation of Platelets through Budding.

Huan Liu, Hellen Ishikawa-Ankerhold, Julia Winterhalter, Michael Lorenz, Mykhailo Vladymyrov, Steffen Massberg, Christian Schulz, Mathias Orban

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Huan LiuDepartment of Internal Medicine I, Ludwig Maximilians University, 81377 Munich, Germany.
Hellen Ishikawa-AnkerholdDepartment of Internal Medicine I, Ludwig Maximilians University, 81377 Munich, Germany.ORCID 0000-0003-0307-7022
Julia WinterhalterDepartment of Internal Medicine I, Ludwig Maximilians University, 81377 Munich, Germany.
Michael LorenzDepartment of Internal Medicine I, Ludwig Maximilians University, 81377 Munich, Germany.
Mykhailo VladymyrovLaboratory for High Energy Physics (LHEP), Albert Einstein Center for Fundamental Physics, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0002-5720-9740
Steffen MassbergDepartment of Internal Medicine I, Ludwig Maximilians University, 81377 Munich, Germany.
Christian SchulzDepartment of Internal Medicine I, Ludwig Maximilians University, 81377 Munich, Germany.ORCID 0000-0002-8149-0747
Mathias OrbanDepartment of Internal Medicine I, Ludwig Maximilians University, 81377 Munich, Germany.ORCID 0000-0001-7846-8808
Ludwig-Maximilians-Universität München · DEGerman Centre for Cardiovascular Research · DEUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platelets are generated by specialized cells called megakaryocytes (MKs). However, MK's origin and platelet release mode have remained incompletely understood. Here, we established direct visualization of embryonic thrombopoiesis in vivo by combining multiphoton intravital microscopy (MP-IVM) with a fluorescence switch reporter mouse model under control of the platelet factor 4 promoter (

Indexed as

MicroscopyThrombopoiesisAnimalsBlood PlateletsMegakaryocytesMicePlatelet Countc-Mybfetal livermegakaryocytemultiphoton intravital microscopythrombopoiesisyolk sac

Identifiers

PMID37830625
PMCPMC10572188
OpenAlexW4387407757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.