Evidence map›Paper›PMID 37830595›Full record

ReviewCells2023

The Present and Future of Optic Pathway Glioma Therapy.

Simone Dal Bello, Deborah Martinuzzi, Yan Tereshko, Daniele Veritti, Valentina Sarao, Gian Luigi Gigli, Paolo Lanzetta, Mariarosaria Valente

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Role of miRNA in adult ocular tumorigenesis.Frontiers in molecular biosciences · 2025
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Simone Dal BelloClinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.ORCID 0000-0003-2062-2547
Deborah MartinuzziDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.
Yan TereshkoClinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.ORCID 0000-0002-4200-761X
Daniele VerittiDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.ORCID 0000-0003-0148-5348
Valentina SaraoDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.ORCID 0000-0003-0041-5073
Gian Luigi GigliDepartment of Medical Area, University of Udine, 33100 Udine, Italy.
Paolo LanzettaDepartment of Medicine-Ophthalmology, University of Udine, 33100 Udine, Italy.ORCID 0000-0003-3746-141X
Mariarosaria ValenteClinical Neurology Unit, Santa Maria della Misericordia University Hospital, 33100 Udine, Italy.
University of Udine · ITOspedale Santa Maria della Misericordia di Udine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optic pathway gliomas (OPGs) encompass two distinct categories: benign pediatric gliomas, which are characterized by favorable prognosis, and malignant adult gliomas, which are aggressive cancers associated with a poor outcome. Our review aims to explore the established standards of care for both types of tumors, highlight the emerging therapeutic strategies for OPG treatment, and propose potential alternative therapies that, while originally studied in a broader glioma context, may hold promise for OPGs pending further investigation. These potential therapies encompass immunotherapy approaches, molecular-targeted therapy, modulation of the tumor microenvironment, nanotechnologies, magnetic hyperthermia therapy, cyberKnife, cannabinoids, and the ketogenic diet. Restoring visual function is a significant challenge in cases where optic nerve damage has occurred due to the tumor or its therapeutic interventions. Numerous approaches, particularly those involving stem cells, are currently being investigated as potential facilitators of visual recovery in these patients.

Indexed as

Brain NeoplasmsHyperthermia, InducedNeurofibromatosis 1Optic Nerve GliomaAdultChildHumansImmunotherapyTumor Microenvironmentglioma therapyimmunomodulationoptic pathway gliomatarget therapyvision recovery

Identifiers

PMID37830595
PMCPMC10572241
OpenAlexW4387170243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.