Evidence map›Paper›PMID 37830580›Full record

ArticleCells2023

Effects of Weight Loss and Aerobic Exercise Training on Adi-Pose Tissue Zinc α2-Glycoprotein and Associated Genes in Obesity.

Shealinna X Ge, Guoyan Li, Alice S Ryan

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Shealinna X GeDepartment of Dermatology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Guoyan LiDivision of Gerontology and Palliative Medicine, Department of Medicine, University of Maryland School of Medicine, 655 W Baltimore Street, Baltimore, MD 21201, USA.
Alice S RyanDivision of Gerontology and Palliative Medicine, Department of Medicine, University of Maryland School of Medicine, 655 W Baltimore Street, Baltimore, MD 21201, USA.
University of Maryland, Baltimore · USGeriatric Research Education and Clinical Center · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D · 2005 to 2019
$17.3M
NIA NIH HHS P30 AG028747NIDDK NIH HHS P30 DK072488RRD VA IK6 RX003977
6 · The paper itself

Abstract

Zinc α2-glycoprotein (ZAG) has been implicated in fatty acid metabolism and utilization and is lower in obese and higher in cachexic adults compared to those of normal weight. Previous studies suggest that ZAG binds to the beta3-adrenergic receptor (β3AR) to influence fatty acid metabolism in adipose tissue by regulating hormone sensitive lipase (HSL). The purpose of this study is to investigate the effects of a six-month weight loss (WL) or aerobic exercise (AEX) intervention on adipose tissue and skeletal muscle ZAG mRNA levels and protein expression, as well as the expression of β3AR, and HSL. Abdominal adipose tissue (AB) and gluteal adipose tissue (Glut) and vastus lateralis muscle biopsies were performed before and after WL (

Indexed as

ExerciseObesityWeight LossBody WeightFatty AcidsGlucoseGlycoproteinsHumansRNA, MessengerZincZn-Alpha-2-GlycoproteinAZGP1 protein, humanFatty AcidsGlucoseGlycoproteinsRNA, MessengerZincZn-Alpha-2-Glycoproteinadipose tissuebody compositionHSLweight loss and exercisesZAGβ3AR

Identifiers

PMID37830580
PMCPMC10571564
OpenAlexW4387101335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.