Evidence map›Paper›PMID 37830493›Full record

ArticleBJPsych open2023

Cost-effectiveness of twice-weekly versus once-weekly sessions of cognitive-behavioural therapy and interpersonal psychotherapy for depression at 12 months after start of treatment: randomised controlled trial.

Judith E Bosmans, Sanne J E Bruijniks, Mohamed El Alili, Steven D Hollon, Frenk P M L Peeters, Arnoud Arntz, Pim Cuijpers, Lotte H J M Lemmens, Pieter Dingemanse, Linda Willems and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJPsych open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Judith E BosmansDepartment of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-1443-1026
Sanne J E BruijniksDepartment of Clinical Psychology and Psychotherapy, University of Freiburg, Germany; and Department of Clinical Psychology, Utrecht University, The Netherlands.ORCID https://orcid.org/0000-0003-3448-5192
Mohamed El AliliDepartment of Health Sciences, Faculty of Science, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, The Netherlands.
Steven D HollonDepartment of Psychology, Vanderbilt University, Tennessee, USA.
Frenk P M L PeetersDepartment of Clinical Psychological Science, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
Arnoud ArntzDepartment of Clinical Psychology, University of Amsterdam, The Netherlands.
Pim CuijpersDepartment of Clinical Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0001-5497-2743
Lotte H J M LemmensDepartment of Clinical Psychological Science, Faculty of Psychology and Neuroscience, Maastricht University, The Netherlands.
Pieter DingemanseDivision of Affective Disorders, Mental Health Care Altrecht, The Netherlands.
Linda WillemsDepartment of Mood Disorders, GGZ Oost-Brabant, The Netherlands.
Patricia van OppenDepartment of Research and Innovation, GGZ InGeest Specialized Mental Health Care, The Netherlands; and Department of Psychiatry, Amsterdam University Medical Centers, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, The Netherlands.
Michael van den BoogaardPsyQ, Parnassia Groep, The Netherlands.
Jan SpijkerDepression Expertise Centre, Pro Persona Mental Health Care, The Netherlands; and Behavioral Science Institute, Radboud University, The Netherlands.ORCID https://orcid.org/0000-0003-1480-9647
Jos W R TwiskDepartment of Epidemiology and Biostatistics, Amsterdam University Medical Centers, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, The Netherlands.
Marcus J H HuibersDepartment of Clinical Psychology and Psychotherapy, University of Freiburg, Germany; and Department of Clinical Psychology, Utrecht University, The Netherlands.

Funding

ZonMw
6 · The paper itself

Abstract

backgroundCost-effective treatments are needed to reduce the burden of depression. One way to improve the cost-effectiveness of psychotherapy might be to increase session frequency, but keep the total number of sessions constant.

aimTo evaluate the cost-effectiveness of twice-weekly compared with once-weekly psychotherapy sessions after 12 months, from a societal perspective.

methodAn economic evaluation was conducted alongside a randomised controlled trial comparing twice-weekly versus once-weekly sessions of psychotherapy (cognitive-behavioural therapy or interpersonal psychotherapy) for depression. Missing data were handled by multiple imputation. Statistical uncertainty was estimated with bootstrapping and presented with cost-effectiveness acceptability curves.

resultsDifferences between the two groups in depressive symptoms, physical and social functioning, and quality-adjusted life-years (QALY) at 12-month follow-up were small and not statistically significant. Total societal costs in the twice-weekly session group were higher, albeit not statistically significantly so, than in the once-weekly session group (mean difference €2065, 95% CI -686 to 5146). The probability that twice-weekly sessions are cost-effective compared with once-weekly sessions was 0.40 at a ceiling ratio of €1000 per point improvement in Beck Depression Inventory-II score, 0.32 at a ceiling ratio of €50 000 per QALY gained, 0.23 at a ceiling ratio of €1000 per point improvement in physical functioning score and 0.62 at a ceiling ratio of €1000 per point improvement in social functioning score.

conclusionsBased on the current results, twice-weekly sessions of psychotherapy for depression are not cost-effective over the long term compared with once-weekly sessions.

Indexed as

cost-effectivenessDepressive disordersindividual psychotherapyout-patient treatmentrandomised controlled trial

Identifiers

PMID37830493
PMCPMC10594223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.