Evidence map›Paper›PMID 37830353›Full record

ArticleJournal of the American Heart Association2023

A Novel Window Into Human Vascular Remodeling and Diagnosing Carotid Flow Impairment: The Petro-Occipital Venous Plexus.

Wenjie Yang, Kevin Sam, Ye Qiao, Zhongqing Huang, David A Steinman, Bruce A Wasserman

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Wenjie YangDepartment of Diagnostic Radiology & Nuclear Medicine University of Maryland School of Medicine Baltimore MD.ORCID 0000-0003-1993-1860
Kevin SamDepartment of Diagnostic Radiology & Nuclear Medicine University of Maryland School of Medicine Baltimore MD.ORCID 0000-0002-1030-752X
Ye QiaoRussell H. Morgan Department of Radiology and Radiological Sciences Johns Hopkins School of Medicine Baltimore MD.ORCID 0000-0002-0499-9283
Zhongqing HuangDepartment of Diagnostic Radiology & Nuclear Medicine University of Maryland School of Medicine Baltimore MD.ORCID 0000-0002-6623-5959
David A SteinmanDepartment of Mechanical & Industrial Engineering University of Toronto Canada.ORCID 0000-0002-7963-1168
Bruce A WassermanDepartment of Diagnostic Radiology & Nuclear Medicine University of Maryland School of Medicine Baltimore MD.ORCID 0000-0001-8458-1778
University of Maryland, Baltimore · USJohns Hopkins University · USUniversity of Toronto · CA

Funding

The Role of Intracranial Atherosclerosis in the Development of Alzheimer's DiseaseR01AG054491 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI WASSERMAN, BRUCE A · 2016 to 2021
$6.4M
NIA NIH HHS R01 AG054491
6 · The paper itself

Abstract

Background Adaptive arterial remodeling caused by flow reduction from downstream stenosis has been demonstrated in animal studies. The authors sought to determine whether inward remodeling from downstream stenosis also occurs in humans and is detectable by ex vacuo expansion of the Rektorzik venous plexus (RVP) surrounding the petrous internal carotid artery. Methods and Results The authors analyzed 214 intracranial magnetic resonance imaging examinations that included contrast-enhanced vessel wall imaging. RVP symmetry was qualitatively assessed on vessel wall imaging. RVP thickness (RVPT) was measured on the thicker side if asymmetric or randomly assigned side if symmetric. Maximum stenosis (M1 or intracranial internal carotid artery) was measured. Posterior communicating artery and A1 diameters (>1.0 mm and 1.5 mm, respectively) defined adequate collateral outflow when proximal to the stenosis. Seventy-two patients had stenosis downstream from RVPT measurements. For those without adequate outflow (38 of 72), 95.0% with RVPT ≥1.0 mm had ≥50% stenosis compared with only 5.6% with RVPT <1.0 mm. For these 72 patients, higher RVPT (RVPT ≥1.0 mm versus <1.0 mm) and absent adequate outflow were associated with greater downstream stenosis (

Indexed as

Carotid StenosisVascular RemodelingCarotid Artery, InternalConstriction, PathologicHumansMagnetic Resonance Imagingblack blood MRIintracranial stenosisRektorzik venous plexusvascular remodelingvessel wall imaging

Identifiers

PMID37830353
PMCPMC10757507
OpenAlexW4387599177

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.